FBXO32 antibody (AA 31-130)

Catalog No. ABIN747698

Product Details anti-FBXO32 Antibody

Target: FBXO32 (F-Box Protein 32 (FBXO32))

Binding Specificity: AA 31-130

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FBXO32 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Cross-Reactivity: Human, Rat

Predicted Reactivity: Mouse,Dog,Cow,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Fbx32

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

References for anti-FBXO32 antibody (ABIN747698)

Lin, Hanson, Betik, Brennan-Speranza, Hayes, Levinger: "Hindlimb Immobilization, But Not Castration, Induces Reduction of Undercarboxylated Osteocalcin Associated With Muscle Atrophy in Rats." in: Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, Vol. 31, Issue 11, pp. 1967-1978, (2016) (PubMed).

Target Details for FBXO32

Target: FBXO32 (F-Box Protein 32 (FBXO32))

Alternative Name: Fbx32 (FBXO32 Products)

Synonyms: MGC56479 antibody, zgc:56479 antibody, Fbx32 antibody, MAFbx antibody, 4833442G10Rik antibody, AI430017 antibody, ATROGIN1 antibody, Gm20361 antibody, Atrogin1 antibody, F-box protein 32 antibody, fbxo32 antibody, FBXO32 antibody, Fbxo32 antibody

Background:

Synonyms: Fbx32, MAFbx, F-box only protein 32, Atrogin-1, Muscle atrophy F-box protein, FBXO32

Background: Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Probably recognizes and binds to phosphorylated target proteins during skeletal muscle atrophy. Recognizes TERF1.

Gene ID: 114907

UniProt: Q969P5