PBK antibody (AA 251-322)

Catalog No. ABIN747608

Product Details anti-PBK Antibody

Target: PBK (PDZ Binding Kinase (PBK))

Binding Specificity: AA 251-322

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PBK antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Cross-Reactivity: Mouse

Predicted Reactivity: Human,Rat,Dog,Cow,Pig

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human PBK

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for PBK

Target: PBK (PDZ Binding Kinase (PBK))

Alternative Name: PBK (PBK Products)

Synonyms: PBK antibody, topk antibody, CT84 antibody, Nori-3 antibody, SPK antibody, TOPK antibody, 2810434B10Rik antibody, AW538537 antibody, D14Ertd732e antibody, zgc:92050 antibody, PDZ binding kinase antibody, PDZ binding kinase L homeolog antibody, PBK antibody, pbk antibody, Pbk antibody, pbk.L antibody

Background:

Synonyms: SPK, CT84, TOPK, HEL164, Nori-3, Lymphokine-activated killer T-cell-originated protein kinase, Cancer/testis antigen 84, MAPKK-like protein kinase, PDZ-binding kinase, Spermatogenesis-related protein kinase, T-LAK cell-originated protein kinase, PBK

Background: Phosphorylates MAP kinase p38. Seems to be active only in mitosis. May also play a role in the activation of lymphoid cells. When phosphorylated, forms a complex with TP53, leading to TP53 destabilization and attenuation of G2/M checkpoint during doxorubicin-induced DNA damage.

Gene ID: 55872

UniProt: Q96KB5