SYCP3 antibody (AA 145-250) (Biotin)

Catalog No. ABIN747385

Product Details anti-SYCP3 Antibody (Biotin)

Target: SYCP3 (Synaptonemal Complex Protein 3 (SYCP3))

Binding Specificity: AA 145-250

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SYCP3 antibody is conjugated to Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Cross-Reactivity: Human, Mouse, Rat

Predicted Reactivity: Dog,Cow,Pig,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human CTDSPL

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for SYCP3

Target: SYCP3 (Synaptonemal Complex Protein 3 (SYCP3))

Alternative Name: SCP3 (SYCP3 Products)

Synonyms: Cor1 antibody, Scp3 antibody, COR1 antibody, SCP3 antibody, SPGF4 antibody, RNASCP3 antibody, SYCP3 antibody, sycp3 antibody, MGC146429 antibody, scp3 antibody, SCP-3 antibody, synaptonemal complex protein 3 antibody, synaptonemal complex protein 3 L homeolog antibody, Sycp3 antibody, SYCP3 antibody, sycp3 antibody, scp3 antibody, sycp3.L antibody

Background:

Synonyms: PSR1, SCP3, HYA22, RBSP3, C3orf8, CTD small phosphatase-like protein, CTDSP-like, Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 3, NIF-like protein, Nuclear LIM interactor-interacting factor 1, NLI-interacting factor 1, Protein YA22, Small C-terminal domain phosphatase 3, Small CTD phosphatase 3, CTDSPL, NIF1, NIFL, YA22

Background: Recruited by REST to neuronal genes that contain RE-1 elements, leading to neuronal gene silencing in non-neuronal cells (By similarity). Preferentially catalyzes the dephosphorylation of 'Ser-5' within the tandem 7 residue repeats in the C-terminal domain (CTD) of the largest RNA polymerase II subunit POLR2A. Negatively regulates RNA polymerase II transcription, possibly by controlling the transition from initiation/capping to processive transcript elongation.

Gene ID: 10217

UniProt: O15194