TNK1 antibody (pTyr277)

Catalog No. ABIN746513

Product Details anti-TNK1 Antibody

Target: TNK1 (Tyrosine Kinase, Non-Receptor, 1 (TNK1))

Binding Specificity: pTyr277

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TNK1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunocytochemistry (ICC)

Specificity: This phosphorylation site is homologous across the listed species.

Cross-Reactivity: Mouse

Predicted Reactivity: Human,Rat,Dog,Pig,Horse,Rabbit,Guinea Pig

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic phosphopeptide derived from human TNK1 around the phosphorylation site of Tyr277 [GR(p-Y)VM]

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for TNK1

Target: TNK1 (Tyrosine Kinase, Non-Receptor, 1 (TNK1))

Alternative Name: TNK1 (TNK1 Products)

Synonyms: Kos1 antibody, Tnk1a antibody, Tnk1b antibody, Ack-like antibody, tyrosine kinase non receptor 1 antibody, tyrosine kinase, non-receptor, 1 antibody, TNK1 antibody, Tnk1 antibody

Background:

Synonyms: Non-receptor tyrosine-protein kinase TNK1, CD38 negative kinase 1, TNK1

Background: Involved in negative regulation of cell growth. Has tumor suppressor properties. Plays a negative regulatory role in the Ras-MAPK pathway. May function in signaling pathways utilized broadly during fetal development and more selectively in adult tissues and in cells of the lymphohematopoietic system. Could specifically be involved in phospholipid signal transduction.

Gene ID: 8711

UniProt: Q13470