PLCB3 antibody (pSer1105) (Biotin)

Catalog No. ABIN744880

Product Details anti-PLCB3 Antibody (Biotin)

Target: PLCB3 (phospholipase C, beta 3 (Phosphatidylinositol-Specific) (PLCB3))

Binding Specificity: pSer1105

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PLCB3 antibody is conjugated to Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Cross-Reactivity: Human

Predicted Reactivity: Mouse,Rat,Dog,Cow,Pig,Horse

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic phosphopeptide derived from human PLC beta3 around the phosphorylation site of Ser1105

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for PLCB3

Target: PLCB3 (phospholipase C, beta 3 (Phosphatidylinositol-Specific) (PLCB3))

Alternative Name: PLC beta3 (PLCB3 Products)

Synonyms: she antibody, Plcbeta3 antibody, wu:fl04b08 antibody, si:zc188c22.1 antibody, si:ch211-188c22.1 antibody, plcb3 antibody, PLCB3 antibody, mKIAA4098 antibody, phospholipase C beta 3 antibody, phospholipase C, beta 3 (phosphatidylinositol-specific) antibody, phospholipase C, beta 3 antibody, PLCB3 antibody, Plcb3 antibody, plcb3 antibody

Background:

Synonyms: Phospholipase C beta 3, Phospholipase C beta 3 phosphatidylinositol specic, PLC beta 3, PLCB3 antibody 1 phosphatidylinositol 4 5 bisphosphate phosphodiesterase beta 3, Phosphoinositide phospholipase C, PLCB3_HUMAN.

Background: Phospholipase C is a key enzyme in phosphatidylinositol (PIP2) metabolism and lipid signaling pathways. The Phospholipase C family consists of 13 isozymes split between six subfamilies. Phospholipase C beta is activated by G protein subunits.

Gene ID: 5331

Pathways: WNT Signaling, Thyroid Hormone Synthesis, Myometrial Relaxation and Contraction, CXCR4-mediated Signaling Events, G-protein mediated Events