NDRG1 antibody (pThr346)

Catalog No. ABIN744233

Product Details anti-NDRG1 Antibody

Target: NDRG1 (N-Myc Downstream Regulated 1 (NDRG1))

Binding Specificity: pThr346

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NDRG1 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Cross-Reactivity: Human, Rat

Predicted Reactivity: Mouse,Dog,Cow,Horse

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic phosphopeptide derived from human NDRG1 around the phosphorylation site of Thr346

Isotype: IgG

Application Details

Application Notes: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for NDRG1

Target: NDRG1 (N-Myc Downstream Regulated 1 (NDRG1))

Alternative Name: NDRG1 (NDRG1 Products)

Synonyms: CAP43 antibody, CMT4D antibody, DRG-1 antibody, DRG1 antibody, GC4 antibody, HMSNL antibody, NDR1 antibody, NMSL antibody, PROXY1 antibody, RIT42 antibody, RTP antibody, TARG1 antibody, TDD5 antibody, Ndr1 antibody, Ndrl antibody, cap43 antibody, cmt4d antibody, drg1 antibody, gc4 antibody, hmsnl antibody, ndr1 antibody, ndrg1 antibody, nmsl antibody, proxy1 antibody, rit42 antibody, rtp antibody, targ1 antibody, tdd5 antibody, xndrg1 antibody, ndrg4 antibody, cb775 antibody, wu:fb60h02 antibody, zgc:63944 antibody, NDRG1 antibody, NON-RACE SPECIFIC DISEASE RESISTANCE PROTEIN antibody, non race-specific disease resistance 1 antibody, ndrg1-a antibody, ndrg1-b antibody, xNDRG1-A antibody, ndrg1l antibody, zgc:73047 antibody, N-myc downstream regulated 1 antibody, N-myc downstream regulated gene 1 antibody, N-myc downstream regulated 1 S homeolog antibody, N-myc downstream regulated 1a antibody, Late embryogenesis abundant (LEA) hydroxyproline-rich glycoprotein family antibody, N-myc downstream regulated 1 L homeolog antibody, N-myc downstream regulated 1b antibody, NDRG1 antibody, Ndrg1 antibody, ndrg1.S antibody, ndrg1 antibody, ndrg1a antibody, NDR1 antibody, ndrg1.L antibody, ndrg1b antibody

Background:

Synonyms: N-myc downstream regulated gene 1, TDD5, 42 kDa, cap43, cmt4d, Dferentiation related gene1 protein, Drg 1, drg1, gc4, hmsnl, Human mRNA for RTP complete cds, N myc downstream regulated gene 1 protein, Ndr 1, NDRG 1, Nickel specic induction protein Cap43, Nmyc downstream regulated gene1, Protein NDRG1, Protein regulated by oxygen 1 , Protein regulated by oxygen1, proxy1, reducin, Reducing agents and tunicamycin responsive protein, rit42, rtp, targ1, tdds, tunicamycin-responsive protein.

Background: This gene is a member of the N-myc downregulated gene family which belongs to the alpha/beta hydrolase superfamily. The protein encoded by this gene is a cytoplasmic protein involved in stress responses, hormone responses, cell growth, and differentiation. Mutation in this gene has been reported to be causative for hereditary motor and sensory neuropathy-Lom. May have a growth inhibitory role. Ubiquitous, expressed most prominently in placental membranes and prostate, kidney, small intestine, and ovary tissues. Reduced expression in adenocarcinomas compared to normal tissues. In colon, prostate and placental membranes, the cells that border the lumen show the highest expression.

Gene ID: 10397