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JAK1 antibody (pTyr1034, pTyr1035)

JAK1 Reactivity: Human, Mouse WB, ELISA, IHC (p), FACS Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN743333
  • Target See all JAK1 Antibodies
    JAK1 (Janus Kinase 1 (JAK1))
    Binding Specificity
    • 15
    • 15
    • 13
    • 11
    • 7
    • 7
    • 6
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pTyr1034, pTyr1035
    Reactivity
    • 105
    • 81
    • 62
    • 2
    • 2
    • 2
    • 2
    Human, Mouse
    Host
    • 86
    • 25
    • 1
    • 1
    Rabbit
    Clonality
    • 86
    • 27
    Polyclonal
    Conjugate
    • 52
    • 8
    • 6
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This JAK1 antibody is un-conjugated
    Application
    • 77
    • 38
    • 29
    • 16
    • 15
    • 14
    • 13
    • 11
    • 8
    • 5
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)
    Cross-Reactivity
    Human, Mouse
    Predicted Reactivity
    Rat,Cow,Pig
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic phosphopeptide derived from human Jak1 around the phosphorylation site of Tyr1034 + Tyr1035
    Isotype
    IgG
    Top Product
    Discover our top product JAK1 Primary Antibody
  • Application Notes
    WB 1:300-5000
    ELISA 1:500-1000
    FCM 1:20-100
    IHC-P 1:200-400
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Expiry Date
    12 months
  • Huang, Zhou, Li, Ming, Li, Wu, Chen, Zhao: "In vivo and in vitro effects of microRNA-221 on hepatocellular carcinoma development and progression through the JAK-STAT3 signaling pathway by targeting SOCS3." in: Journal of cellular physiology, Vol. 234, Issue 4, pp. 3500-3514, (2019) (PubMed).

    Iriyama, Hatta, Takei: "Direct effect of dasatinib on signal transduction pathways associated with a rapid mobilization of cytotoxic lymphocytes." in: Cancer medicine, Vol. 5, Issue 11, pp. 3223-3234, (2016) (PubMed).

  • Target
    JAK1 (Janus Kinase 1 (JAK1))
    Alternative Name
    Jak1 + (JAK1 Products)
    Synonyms
    JAK1A antibody, JAK1B antibody, JTK3 antibody, AA960307 antibody, C130039L05Rik antibody, wu:fb93e10 antibody, jak1 antibody, Janus kinase 1 antibody, tyrosine-protein kinase JAK1 antibody, JAK1 antibody, Jak1 antibody, jak1 antibody, LOC100286690 antibody
    Background

    Synonyms: Tyrosine-protein kinase JAK1, Janus kinase 1, JAK-1, JAK1, JAK1A, JAK1B

    Background: Tyrosine kinase of the non-receptor type, involved in the IFN-alpha/beta/gamma signal pathway. Kinase partner for the interleukin (IL)-2 receptor.

    Gene ID
    3716
    UniProt
    P23458
    Pathways
    JAK-STAT Signaling, RTK Signaling, Interferon-gamma Pathway, Hepatitis C, Toll-Like Receptors Cascades, Unfolded Protein Response
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