IGSF8 antibody (AA 101-200) (Biotin)

Catalog No. ABIN742397

Product Details anti-IGSF8 Antibody (Biotin)

Target: IGSF8 (Immunoglobulin Superfamily, Member 8 (IGSF8))

Binding Specificity: AA 101-200

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IGSF8 antibody is conjugated to Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Cross-Reactivity: Human, Mouse

Predicted Reactivity: Rat,Cow,Pig,Horse

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from mouse IGSF8

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for IGSF8

Target: IGSF8 (Immunoglobulin Superfamily, Member 8 (IGSF8))

Alternative Name: IGSF8/CD316 (IGSF8 Products)

Synonyms: MGC77222 antibody, IGSF8 antibody, MGC151661 antibody, CD316 antibody, CD81P3 antibody, EWI-2 antibody, EWI2 antibody, KCT-4 antibody, LIR-D1 antibody, PGRL antibody, AA033172 antibody, AU041109 antibody, ESTM34 antibody, R75384 antibody, immunoglobulin superfamily, member 8 antibody, immunoglobulin superfamily member 8 antibody, igsf8 antibody, IGSF8 antibody, Igsf8 antibody

Background:

Synonyms: PGRL, EWI-2, KCT-4, ESTM34, R75384, AA033172, AU041109, Immunoglobulin superfamily member 8, IgSF8, CD81 partner 3, Glu-Trp-Ile EWI motif-containing protein 2, Keratinocyte-associated transmembrane protein 4, Prostaglandin regulatory-like protein, CD316, Ewi2, Kct4

Background: May play a key role in diverse functions ascribed to CD81 and CD9 such as oocytes fertilization or hepatitis C virus function. May regulate proliferation and differentiation of keratinocytes. May be a negative regulator of cell motility: suppresses T-cell mobility coordinately with CD81, associates with CD82 to suppress prostate cancer cell migration, regulates epidermoid cell reaggregation and motility on laminin-5 with CD9 and CD81 as key linkers. May also play a role on integrin-dependent morphology and motility functions. May participate in the regulation of neurite outgrowth and maintenance of the neural network in the adult brain.

Gene ID: 140559

UniProt: Q8R366