CXCL13 antibody (AA 23-109)

Catalog No. ABIN741960

Product Details anti-CXCL13 Antibody

Target: CXCL13 (Chemokine (C-X-C Motif) Ligand 13 (CXCL13))

Binding Specificity: AA 23-109

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CXCL13 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Cross-Reactivity: Human, Mouse

Predicted Reactivity: Dog

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human CXCL13

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

References for anti-CXCL13 antibody (ABIN741960)

Li, Cao, Wang, Jia, He, Zhang: "Up-regulation of chemokine CXCL13 in systemic candidiasis." in: Clinical immunology (Orlando, Fla.), (2018) (PubMed).

Lemma, Pasanen, Haapasaari, Sippola, Sormunen, Soini, Jantunen, Koivunen, Salokorpi, Bloigu, Turpeenniemi-Hujanen, Kuittinen: "Similar chemokine receptor profiles in lymphomas with central nervous system involvement - possible biomarkers for patient selection for central nervous system prophylaxis, a retrospective study." in: European journal of haematology, (2015) (PubMed).

Nakamura, Ito, Kobayashi, Herndon, Suzuki: "Orosomucoid 1 drives opportunistic infections through the polarization of monocytes to the M2b phenotype." in: Cytokine, Vol. 73, Issue 1, pp. 8-15, (2015) (PubMed).

Pei, Zeng, Han, Liao, Zhou, Li, Zhang, Liu, Zhang, Liu, Yao, Xu: "Renal interstitial infiltration and tertiary lymphoid organ neogenesis in IgA nephropathy." in: Clinical journal of the American Society of Nephrology : CJASN, Vol. 9, Issue 2, pp. 255-64, (2014) (PubMed).

Pimenta, De, Weiss, Feng, Hall, Kilic, Bhanot, Ganesan, Ran, Barnes: "IRF5 is a novel regulator of CXCL13 expression in breast cancer that regulates CXCR5(+) B- and T-cell trafficking to tumor-conditioned media." in: Immunology and cell biology, (2014) (PubMed).

Target Details for CXCL13

Target: CXCL13 (Chemokine (C-X-C Motif) Ligand 13 (CXCL13))

Alternative Name: CXCL13/BCA1 (CXCL13 Products)

Synonyms: 4631412M08Rik antibody, ANGIE2 antibody, Angie antibody, BCA-1 antibody, BLC antibody, BLR1L antibody, Scyb13 antibody, ANGIE antibody, BCA1 antibody, SCYB13 antibody, C-X-C motif chemokine ligand 13 antibody, chemokine (C-X-C motif) ligand 13 antibody, Cxcl13 antibody, CXCL13 antibody

Background:

Synonyms: BLC, BCA1, ANGIE, BCA-1, BLR1L, ANGIE2, SCYB13, C-X-C motif chemokine 13, B cell-attracting chemokine 1, B lymphocyte chemoattractant, CXC chemokine BLC, Small-inducible cytokine B13, CXCL13

Background: Chemotactic for B-lymphocytes but not for T-lymphocytes, monocytes and neutrophils. Does not induce calcium release in B-lymphocytes. Binds to BLR1/CXCR5.

Gene ID: 10563

UniProt: O43927