TRIM63 antibody (AA 251-353) (Biotin)

Catalog No. ABIN741752

Product Details anti-TRIM63 Antibody (Biotin)

Target: TRIM63 (Tripartite Motif Containing 63 (TRIM63))

Binding Specificity: AA 251-353

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TRIM63 antibody is conjugated to Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Cross-Reactivity: Human, Mouse, Rat

Predicted Reactivity: Cow,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human MuRF1/Trim63

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for TRIM63

Target: TRIM63 (Tripartite Motif Containing 63 (TRIM63))

Alternative Name: MuRF1/Trim63 (TRIM63 Products)

Synonyms: IRF antibody, MURF1 antibody, MURF2 antibody, RNF28 antibody, SMRZ antibody, Murf antibody, Murf1 antibody, Rnf28 antibody, MuRF1 antibody, RF1 antibody, rnf30 antibody, MGC80210 antibody, TRIM63 antibody, MuRF antibody, fc50c07 antibody, trim63 antibody, wu:fc50c07 antibody, zgc:86757 antibody, tripartite motif containing 63 antibody, tripartite motif-containing 63 antibody, tripartite motif containing 63 S homeolog antibody, tripartite motif containing 63a antibody, TRIM63 antibody, Trim63 antibody, trim63.S antibody, trim63a antibody

Background:

Synonyms: MuRF 1, MuRF-1, Muscle-specic RING finger protein 1, Muscle-specic RING finger protein 1, E3 ubiquitin-protein ligase TRIM63, FLJ32380, IRF, MURF1, MURF 1, MURF2, RNF28, SMRZ, Iris ring finger protein, Muscle specic ring finger protein 2, Ring finger protein 28, RNF28, SMRZ, Striated muscle RING zinc finger protein, TRIM 63, TRIM63, Tripartite mot containing 63, Tripartite mot containing protein 63, Ubiquitin ligase TRIM63.

Background: This gene encodes a member of the RING zinc finger protein family found in striated muscle and iris. The product of this gene is localized to the Z-line and M-line lattices of myofibrils, where titin's N-terminal and C-terminal regions respectively bind to the sarcomere. In vitro binding studies have shown that this protein also binds directly to titin near the region of titin containing kinase activity. Another member of this protein family binds to microtubules. Since these family members can form heterodimers, this suggests that these proteins may serve as a link between titin kinase and microtubule-dependent signal pathways in muscle. [provided by RefSeq].

Gene ID: 84676