AIMP2 antibody (AA 201-300)

Catalog No. ABIN741300

Product Details anti-AIMP2 Antibody

Target: AIMP2 (Aminoacyl tRNA Synthetase Complex-Interacting Multifunctional Protein 2 (AIMP2))

Binding Specificity: AA 201-300

Reactivity: Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This AIMP2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Cross-Reactivity: Mouse, Rat

Predicted Reactivity: Human,Cow,Pig,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human AIMP2

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

References for anti-AIMP2 antibody (ABIN741300)

Du, Su, Ye, Wang, Huang, Gong: "Pinellia ternata Attenuates Mucus Secretion and Airway Inflammation after Inhaled Corticosteroid Withdrawal in COPD Rats." in: The American journal of Chinese medicine, Vol. 44, Issue 5, pp. 1027-41, (2016) (PubMed).

Target Details for AIMP2

Target: AIMP2 (Aminoacyl tRNA Synthetase Complex-Interacting Multifunctional Protein 2 (AIMP2))

Alternative Name: AIMP2 (AIMP2 Products)

Synonyms: jtv1 antibody, MGC53242 antibody, pro0992 antibody, JTV1 antibody, JTV-1 antibody, P38 antibody, AA407136 antibody, AA407225 antibody, Aimp2(p38) antibody, Jtv1 antibody, aminoacyl tRNA synthetase complex-interacting multifunctional protein 2 L homeolog antibody, aminoacyl tRNA synthetase complex-interacting multifunctional protein 2 antibody, aminoacyl tRNA synthetase complex interacting multifunctional protein 2 antibody, aimp2.L antibody, aimp2 antibody, AIMP2 antibody, Aimp2 antibody

Background:

Synonyms: P38, JTV1, JTV-1, PRO0992, Aminoacyl tRNA synthase complex-interacting multifunctional protein 2, Multisynthase complex auxiliary component p38, Protein JTV-1, AIMP2

Background: Required for assembly and stability of the aminoacyl-tRNA synthase complex. Mediates ubiquitination and degradation of FUBP1, a transcriptional activator of MYC, leading to MYC down-regulation which is required for aveolar type II cell differentiation. Blocks MDM2-mediated ubiquitination and degradation of p53/TP53. Functions as a proapoptotic factor.

Gene ID: 7965

UniProt: Q13155