CCL19 antibody (AA 26-108)

Catalog No. ABIN740505

Product Details anti-CCL19 Antibody

Target: CCL19 (Chemokine (C-C Motif) Ligand 19 (CCL19))

Binding Specificity: AA 26-108

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CCL19 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Cross-Reactivity: Human, Rat

Predicted Reactivity: Mouse,Pig

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from mouse CCL19

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

References for anti-CCL19 antibody (ABIN740505)

Borrelli, Abrão, Taube, Darb-Esfahani, Köhler, Kaufmann, Chiantera, Mechsner: "Immunohistochemical Investigation of Metastasis-Related Chemokines in Deep-Infiltrating Endometriosis and Compromised Pelvic Sentinel Lymph Nodes." in: Reproductive sciences (Thousand Oaks, Calif.), (2015) (PubMed).

Target Details for CCL19

Target: CCL19 (Chemokine (C-C Motif) Ligand 19 (CCL19))

Alternative Name: CCL19/MIP-3 beta (CCL19 Products)

Synonyms: CKb11 antibody, ELC antibody, MIP-3b antibody, MIP3B antibody, SCYA19 antibody, CCL19 antibody, Scya19 antibody, exodus-3 antibody, C-C motif chemokine ligand 19 antibody, chemokine (C-C motif) ligand 19 antibody, CCL19 antibody, ccl19 antibody, Ccl19 antibody

Background:

Synonyms: ELC, CKb11, MIP3B, Scya19, exodus-3, C-C motif chemokine 19, Epstein-Barr virus-induced molecule 1 ligand chemokine, EBI1 ligand chemokine, Small-inducible cytokine A19, Ccl19

Background: Strongly chemotactic for naive (L-selectinhi) CD4 T-cells and for CD8 T-cells and weakly attractive for resting B-cells and memory (L-selectinlo) CD4 T-cells. May play a role in promoting encounters between recirculating T-cells and dendritic cells and in the migration of activated B-cells into the T-zone of secondary lymphoid tissues. Binds to chemokine receptor CCR7. Binds to atypical chemokine receptor ACKR4 and mediates the recruitment of beta-arrestin (ARRB1/2) to ACKR4.

Gene ID: 24047

UniProt: O70460

Pathways: Positive Regulation of Immune Effector Process