Pleiotrophin antibody (AA 101-168)

Catalog No. ABIN740370

Product Details anti-Pleiotrophin Antibody

Target: Pleiotrophin (PTN)

Binding Specificity: AA 101-168

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Pleiotrophin antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Predicted Reactivity: Human,Mouse,Rat,Cow,Pig,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human PTN

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for Pleiotrophin

Target: Pleiotrophin (PTN)

Alternative Name: Pleiotrophin (PTN Products)

Synonyms: zHBNF antibody, zgc:111787 antibody, harp antibody, hbnf antibody, X-PTF antibody, hbgf8 antibody, negf1 antibody, ptn antibody, PTN antibody, HARP antibody, HBGF8 antibody, HBNF antibody, NEGF1 antibody, PTN-A antibody, HB-GAM antibody, HBBM antibody, HBGF-8 antibody, OSF-1 antibody, HBBN antibody, OSF antibody, Osf-1 antibody, Osf1 antibody, Hbnf antibody, pleiotrophin antibody, pleiotrophin L homeolog antibody, ptn antibody, PTN antibody, ptn.L antibody, Ptn antibody

Background:

Synonyms: pleiotrophin, HARP, HBBM, HBGAM, HBGF8, HBNF, HBNF1, Heparin Binding Growth Factor 8, Heparin binding neurite outgrowth promoting factor 1, heparin-binding growth associated molecule, NEGF1, Neurite Growth Promoting Factor 1, OSF-1, osteoblast-specic factor, PTN, PTN_HUMAN.

Background: Pleiotrophin is a heparin-binding growth factor involved in the differentiation and proliferation of neuronal tissue during embryogenesis, and also secreted by melanoma and breast carcinoma cells. Pleiotrophin exhibits mitogenic and angiogenic properties and has been shown to influence the vascular supply, expansion and metastasis of tumour cells.

Gene ID: 5764

Pathways: RTK Signaling