DLK1 antibody (AA 251-350)

Catalog No. ABIN740055

Product Details anti-DLK1 Antibody

Target: DLK1 (delta-Like 1 Homolog (Drosophila) (DLK1))

Binding Specificity: AA 251-350

Reactivity: Human, Mouse, Rat, Sheep

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DLK1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Cross-Reactivity: Human, Mouse, Rat, Sheep

Predicted Reactivity: Pig,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from mouse DLK1

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IF(IHC-P) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

References for anti-DLK1 antibody (ABIN740055)

Peng, Jia, Li, Xie, Xie, Zheng: "Expression of Pref-1 and Related Chemokines during theDevelopment of Rat Mesenteric Lymph Nodes." in: Biomedical and environmental sciences : BES, Vol. 31, Issue 7, pp. 507-514, (2018) (PubMed).

Target Details for DLK1

Target: DLK1 (delta-Like 1 Homolog (Drosophila) (DLK1))

Alternative Name: DLK1 (DLK1 Products)

Synonyms: DELTA1 antibody, DL1 antibody, Delta antibody, DLK antibody, DLK-1 antibody, Delta1 antibody, FA1 antibody, PREF1 antibody, Pref-1 antibody, ZOG antibody, pG2 antibody, AW742678 antibody, DlkI antibody, Ly107 antibody, Peg9 antibody, SCP1 antibody, pref-1 antibody, Zog antibody, delta like canonical Notch ligand 1 antibody, delta like non-canonical Notch ligand 1 antibody, delta-like 1 homolog (Drosophila) antibody, delta-like 1 (Drosophila) antibody, DLL1 antibody, DLK1 antibody, Dll1 antibody, Dlk1 antibody

Background:

Synonyms: DLK, FA1, ZOG, pG2, DLK-1, PREF1, Delta1, Pref-1, Protein delta homolog 1, DLK1

Background: This gene encodes a transmembrane protein containing six epidermal growth factor repeats. The protein is involved in the differentiation of several cell types, including adipocytes, it is also thought to be a tumor suppressor. It is one of several imprinted genes located in a region of on chr 14q32. Certain mutations in this imprinted region can cause phenotypes similar to maternal and paternal uniparental disomy of chromosome 14 (UPD14). This gene is expressed from the paternal allele. A polymorphism within this gene has been associated with child and adolescent obesity. The mode of inheritance for this polymorphism is polar overdominance, this non-Mendelian inheritance pattern was first described in sheep with the callipyge phenotype, which is characterized by muscle hypertrophy and decreased fat mass. [provided by RefSeq, Mar 2010].

Gene ID: 8788

UniProt: P80370