KLRC2 antibody

Catalog No. ABIN739950

Product Details anti-KLRC2 Antibody

Target: KLRC2 (Killer Cell Lectin-Like Receptor Subfamily C, Member 2 (KLRC2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KLRC2 antibody is un-conjugated

Application: ELISA, Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Cross-Reactivity: Monkey

Predicted Reactivity: Human

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human NKG2C

Isotype: IgG

Application Details

Application Notes: WB(1:100-500)
Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for KLRC2

Target: KLRC2 (Killer Cell Lectin-Like Receptor Subfamily C, Member 2 (KLRC2))

Alternative Name: NKG2C (KLRC2 Products)

Synonyms: CD159c antibody, NKG2-C antibody, NKG2C antibody, killer cell lectin like receptor C2 antibody, killer cell lectin-like receptor subfamily C, member 2 antibody, KLRC2 antibody

Background:

Synonyms: KLRC1, NKG2-A/NKG2-B type II integral membrane protein, CD159a, NKG2-A/B-activating NK receptor, NK cell receptor A, NKG2A, NKG2B, KLRC2, NKG2-C type II integral membrane protein, CD159c, NK cell receptor C, NKG2-C-activating NK receptor, NKG2C, KLRC3, NKG2-E type II integral membrane protein, NK cell receptor E, NKG2-E-activating NK receptor, NKG2E, KLRC4, NKG2-F type II integral membrane protein, NK cell receptor F, NKG2-F-activating NK receptor, NKG2F.

Background: Natural killer (NK) cells are lymphocytes that can mediate the lysis of certain tumor cells and virus infected cells without being previously activated. They can also regulate specific humoral and cell mediated immunity. NK cells preferentially express several calcium dependent (C type) lectins, which have been implicated in the regulation of NK cell function. The group, designated KLRC (NKG2) are expressed primarily in natural killer (NK) cells and encodes a family of transmembrane proteins characterized by a type II membrane orientation (extracellular C terminus) and the presence of a C type lectin domain. The KLRC (NKG2) gene family is located within the NK complex, a region that contains several C type lectin genes preferentially expressed on NK cells.

Molecular Weight: 25kDa

Gene ID: 3822

UniProt: P26717