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GM1123 antibody (AA 21-120)

GM1123 Reactivity: Human, Mouse, Rat WB, FACS, IF (cc), IF (p), IHC (fro), IHC (p), ELISA Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN739575
  • Target See all GM1123 products
    GM1123 (Predicted Gene 1123 (GM1123))
    Binding Specificity
    AA 21-120
    Reactivity
    • 18
    • 18
    • 18
    • 3
    • 3
    • 3
    Human, Mouse, Rat
    Host
    • 18
    Rabbit
    Clonality
    • 18
    Polyclonal
    Conjugate
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This GM1123 antibody is un-conjugated
    Application
    Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), ELISA
    Cross-Reactivity
    Human, Mouse, Rat
    Predicted Reactivity
    Dog,Cow,Pig,Horse,Rabbit
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human Coxsackie Adenovirus Receptor
    Isotype
    IgG
  • Application Notes
    WB 1:300-5000
    ELISA 1:500-1000
    FCM 1:20-100
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Expiry Date
    12 months
  • Target
    GM1123 (Predicted Gene 1123 (GM1123))
    Alternative Name
    Coxsackie Adenovirus Receptor (GM1123 Products)
    Synonyms
    AV052824 antibody, CLSP antibody, predicted gene 1123 antibody, coxsackie virus and adenovirus receptor-like 1-like antibody, Gm1123 antibody, LOC100359797 antibody
    Background

    Synonyms: CAR, HCAR, CAR4/6, Coxsackievirus and adenovirus receptor, CVB3-binding protein, Coxsackievirus B-adenovirus receptor, HCVADR, CXADR

    Background: Component of the epithelial apical junction complex that may function as an homophilic cell adhesion molecule and is essential for tight junction integrity. Also involved in transepithelial migration of leukocytes through adhesive interactions with AMICA1/JAML a transmembrane protein of the plasma membrane of leukocytes. The interaction between both receptors also mediates the activation of gamma-delta T-cells, a subpopulation of T-cells residing in epithelia and involved in tissue homeostasis and repair. Upon epithelial CXADR-binding, AMICA1 induces downstream cell signaling events in gamma-delta T-cells through PI3-kinase and MAP kinases. It results in proliferation and production of cytokines and growth factors by T-cells that in turn stimulate epithelial tissues repair.

    Gene ID
    1525
    UniProt
    P78310
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