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KLF2/4 antibody (AA 415-513) (Biotin)

KLF2/4 Reactivity: Human, Mouse, Rat WB, IHC (fro), IHC (p), ELISA Host: Rabbit Polyclonal Biotin
Catalog No. ABIN737123
  • Target See all KLF2/4 products
    KLF2/4 (Kruppel-Like Factor 2/4 (KLF2/4))
    Binding Specificity
    AA 415-513
    Reactivity
    Human, Mouse, Rat
    Host
    • 15
    Rabbit
    Clonality
    • 15
    Polyclonal
    Conjugate
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This KLF2/4 antibody is conjugated to Biotin
    Application
    • 15
    • 14
    • 13
    • 13
    • 2
    • 2
    • 2
    Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), ELISA
    Specificity
    This antibody may crossreact with KLF2 due to high sequence similarity.
    Cross-Reactivity
    Human, Mouse, Rat
    Predicted Reactivity
    Cow,Sheep,Pig,Horse,Chicken,Guinea Pig
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human KLF4
    Isotype
    IgG
  • Application Notes
    WB 1:300-5000
    IHC-P 1:200-400
    IHC-F 1:100-500
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C for 12 months.
    Expiry Date
    12 months
  • Target
    KLF2/4 (Kruppel-Like Factor 2/4 (KLF2/4))
    Abstract
    KLF2/4 Products
    Background

    Synonyms: EZF, GKLF, Krueppel-like factor 4, Epithelial zinc finger protein EZF, Gut-enriched krueppel-like factor, KLF4

    Background: Transcription factor, can act both as activator and as repressor. Binds the 5'-CACCC-3' core sequence. Binds to the promoter region of its own gene and can activate its own transcription. Regulates the expression of key transcription factors during embryonic development. Plays an important role in maintaining embryonic stem cells, and in preventing their differentiation. Required for establishing the barrier function of the skin and for postnatal maturation and maintenance of the ocular surface. Involved in the differentiation of epithelial cells and may also function in skeletal and kidney development. Contributes to the down-regulation of p53/TP53 transcription.

    Gene ID
    9314
    UniProt
    O43474
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