KLF2/4 antibody (AA 415-513) (Biotin)
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- Target See all KLF2/4 products
- KLF2/4 (Kruppel-Like Factor 2/4 (KLF2/4))
- Binding Specificity
- AA 415-513
- Reactivity
- Human, Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This KLF2/4 antibody is conjugated to Biotin
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Application
- Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), ELISA
- Specificity
- This antibody may crossreact with KLF2 due to high sequence similarity.
- Cross-Reactivity
- Human, Mouse, Rat
- Predicted Reactivity
- Cow,Sheep,Pig,Horse,Chicken,Guinea Pig
- Purification
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human KLF4
- Isotype
- IgG
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anti-Kruppel-Like Factor 2/4 (KLF2/4) (AA 415-513) antibody
KLF2/4 Reactivity: Human, Mouse, Rat WB, FACS, IF (cc), IF (p), IHC (fro), IHC (p), ELISA Host: Rabbit Polyclonal unconjugated
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- Application Notes
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WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C for 12 months.
- Expiry Date
- 12 months
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- Target
- KLF2/4 (Kruppel-Like Factor 2/4 (KLF2/4))
- Abstract
- KLF2/4 Products
- Background
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Synonyms: EZF, GKLF, Krueppel-like factor 4, Epithelial zinc finger protein EZF, Gut-enriched krueppel-like factor, KLF4
Background: Transcription factor, can act both as activator and as repressor. Binds the 5'-CACCC-3' core sequence. Binds to the promoter region of its own gene and can activate its own transcription. Regulates the expression of key transcription factors during embryonic development. Plays an important role in maintaining embryonic stem cells, and in preventing their differentiation. Required for establishing the barrier function of the skin and for postnatal maturation and maintenance of the ocular surface. Involved in the differentiation of epithelial cells and may also function in skeletal and kidney development. Contributes to the down-regulation of p53/TP53 transcription.
- Gene ID
- 9314
- UniProt
- O43474
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