SPATA12 antibody (AA 1-100)

Catalog No. ABIN736058

Product Details anti-SPATA12 Antibody

Target: SPATA12 (Spermatogenesis Associated 12 (SPATA12))

Binding Specificity: AA 1-100

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SPATA12 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Predicted Reactivity: Human

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human SPATA12

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

References for anti-SPATA12 antibody (ABIN736058)

Zhang, Yang, Lin, Rong, Liu, Li: "SPATA12 and its possible role in DNA damage induced by ultraviolet-C." in: PLoS ONE, Vol. 8, Issue 10, pp. e78201, (2013) (PubMed).

Target Details for SPATA12

Target: SPATA12 (Spermatogenesis Associated 12 (SPATA12))

Alternative Name: SRG5/SPATA12 (SPATA12 Products)

Synonyms: SRG5 antibody, spermatogenesis associated 12 antibody, SPATA12 antibody

Background:

Synonyms: SRG5, Spermatogenesis-associated protein 12, Spermatogenesis-related protein 5, SPATA12

Background: SPATA12, also known as SRG5 (Spermatogenesis-related protein 5), is a 190 amino acid protein that may be involved in the regulation of spermatogenesis. SPATA12 is expressed in normal adult testis, but is absent in fetal testis, implying that it may be involved in the development of testicular maturation. Specifically, SPATA12 is expressed in spermatocytes, spermatids and spermatozoa, with no expression in Leydig and Sertoli cells. Studies with HeLa and GC-1 germ cells indicate that expression of the SPATA12 gene may delay the progression of G1 to S in the cell cycle, therefore it is thought that SPATA12 maintains the cell in a differentiated state and suppresses cell proliferation.

Gene ID: 353324

UniProt: Q7Z6I5