PEG3 antibody (AA 1501-1588)

Catalog No. ABIN735653

Product Details anti-PEG3 Antibody

Target: PEG3 (Paternally Expressed 3 (PEG3))

Binding Specificity: AA 1501-1588

Reactivity: Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PEG3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Cross-Reactivity: Mouse, Rat

Predicted Reactivity: Human,Cow,Horse

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human PEG3

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

References for anti-PEG3 antibody (ABIN735653)

Yao, Norris, Mason, Strickland: "Laminin regulates PDGFRβ(+) cell stemness and muscle development." in: Nature communications, Vol. 7, pp. 11415, (2016) (PubMed).

Ge, Liang, Luo, Wei, Han, Schatten, Sun, Zhang: "Diabetic uterus environment may play a key role in alterations of DNA methylation of several imprinted genes at mid-gestation in mice." in: Reproductive biology and endocrinology : RB&E, Vol. 11, Issue 1, pp. 119, (2014) (PubMed).

Target Details for PEG3

Target: PEG3 (Paternally Expressed 3 (PEG3))

Alternative Name: PEG3 (PEG3 Products)

Synonyms: PW1 antibody, ZKSCAN22 antibody, ZNF904 antibody, ZSCAN24 antibody, AL022617 antibody, ASF-1 antibody, End4 antibody, Gcap4 antibody, Pw1 antibody, Zfp102 antibody, mKIAA0287 antibody, PEG3 antibody, paternally expressed 3 antibody, paternally-expressed gene 3 protein antibody, PEG3 antibody, Peg3 antibody, LOC100448879 antibody

Background:

Synonyms: PW1, ZNF94, ZSCAN24, ZKSCAN22, Paternally-expressed gene 3 protein, Zinc finger and SCAN domain-containing protein 24, PEG3, KIAA287

Background: Induces apoptosis in cooperation with SIAH1A. Acts as a mediator between p53/TP53 and BAX in a neuronal death pathway that is activated by DNA damage. Acts synergistically with TRAF2 and inhibits TNF induced apoptosis through activation of NF-kappa-B (By similarity). Possesses a tumor suppressing activity in glioma cells.

Gene ID: 5178

UniProt: Q9GZU2