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MMP12 antibody (AA 201-300)

MMP12 Reactivity: Human, Mouse WB, ELISA, IHC (p) Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN735413
  • Target See all MMP12 Antibodies
    MMP12 (Matrix Metallopeptidase 12 (Macrophage Elastase) (MMP12))
    Binding Specificity
    • 9
    • 8
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 201-300
    Reactivity
    • 71
    • 35
    • 32
    • 4
    • 1
    Human, Mouse
    Host
    • 88
    • 3
    • 2
    • 1
    Rabbit
    Clonality
    • 83
    • 11
    Polyclonal
    Conjugate
    • 34
    • 16
    • 13
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This MMP12 antibody is un-conjugated
    Application
    • 78
    • 34
    • 30
    • 10
    • 9
    • 9
    • 6
    • 5
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Cross-Reactivity
    Human, Mouse
    Predicted Reactivity
    Rat
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from rat MMP12
    Isotype
    IgG
    Top Product
    Discover our top product MMP12 Primary Antibody
  • Application Notes
    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Expiry Date
    12 months
  • Hashimoto, Zaima, Sekiguchi, Kugo, Miyamoto, Hoshino, Kawasaki, Sutoh, Usumi, Moriyama: "Dietary DNA Attenuates the Degradation of Elastin Fibers in the Aortic Wall in Nicotine-Administrated Mice." in: Journal of nutritional science and vitaminology, Vol. 64, Issue 4, pp. 271-276, (2019) (PubMed).

    Kugo, Zaima, Onozato, Miyamoto, Hashimoto, Yanagimoto, Moriyama: "Suppressive effects of dietary EPA-rich fish oil on the degradation of elastin fibers in the aortic wall in nicotine-administered mice." in: Food & function, Vol. 8, Issue 8, pp. 2829-2835, (2017) (PubMed).

  • Target
    MMP12 (Matrix Metallopeptidase 12 (Macrophage Elastase) (MMP12))
    Alternative Name
    MMP-12 (MMP12 Products)
    Synonyms
    MMP12 antibody, AV378681 antibody, Mmel antibody, Mme antibody, HME antibody, ME antibody, MME antibody, MMP-12 antibody, matrix metallopeptidase 12 antibody, MMP12 antibody, Mmp12 antibody
    Background

    Synonyms: Mme, Macrophage metalloelastase, Matrix metalloproteinase-12, MMP-12, Mmp12, Mmel

    Background: May be involved in tissue injury and remodeling. Has significant elastolytic activity. Can accept large and small amino acids at the P1' site, but has a preference for leucine. Aromatic or hydrophobic residues are preferred at the P1 site, with small hydrophobic residues (preferably alanine) occupying P3 (By similarity).

    Gene ID
    117033
    UniProt
    Q63341
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