ECE2 antibody (AA 601-700)

Catalog No. ABIN733958

Product Details anti-ECE2 Antibody

Target: ECE2 (Endothelin Converting Enzyme 2 (ECE2))

Binding Specificity: AA 601-700

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ECE2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Cross-Reactivity: Human, Mouse, Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human ECE2

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

References for anti-ECE2 antibody (ABIN733958)

Esposito, Sarnelli, Capoccia, Cirillo, Pesce, Lu, Calì, Cuomo, Steardo: "Autologous transplantation of intestine-isolated glia cells improves neuropathology and restores cognitive deficits in β amyloid-induced neurodegeneration." in: Scientific reports, Vol. 6, pp. 22605, (2016) (PubMed).

Target Details for ECE2

Target: ECE2 (Endothelin Converting Enzyme 2 (ECE2))

Alternative Name: ECE2 (ECE2 Products)

Synonyms: ECE2 antibody, 1810009K13Rik antibody, 6330509A19Rik antibody, 9630025D12Rik antibody, BB127715 antibody, endothelin converting enzyme 2 antibody, endothelin-converting enzyme 2 antibody, ECE2 antibody, LOC702851 antibody, ece2 antibody, LOC100543478 antibody, Ece2 antibody

Background:

Synonyms: EEF1AKMT4-ECE2 readthrough transcript protein, Methyltransferase-like region, Endothelin-converting enzyme 2 region, EEF1AKMT4-ECE2, EFCE2_HUMAN

Background: Converts big endothelin-1 to endothelin-1. May also have methyltransferase activity (By similarity). May play a role in amyloid-beta processing (By similarity).

Gene ID: 110599583, 9718

UniProt: P0DPD8

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling