Cyclin F antibody (AA 451-550)

Catalog No. ABIN732968

Product Details anti-Cyclin F Antibody

Target: Cyclin F (CCNF)

Binding Specificity: AA 451-550

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Cyclin F antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Cross-Reactivity: Human, Rat

Predicted Reactivity: Mouse,Dog,Cow,Pig,Horse,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Cyclin F

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for Cyclin F

Target: Cyclin F (CCNF)

Alternative Name: Cyclin F (CCNF Products)

Synonyms: Cyclin-F antibody, DKFZp459P0432 antibody, FBX1 antibody, FBXO1 antibody, CycF antibody, Fbxo1 antibody, cb443 antibody, zgc:77240 antibody, cyclin F antibody, cyclin F L homeolog antibody, CCNF antibody, ccnf.L antibody, ccnf antibody, Ccnf antibody

Background:

Synonyms: FBX1, FBXO1, Cyclin-F, F-box only protein 1, CCNF

Background: Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of CP110 during G2 phase, thereby acting as an inhibitor of centrosome reduplication.

Gene ID: 899

UniProt: P41002