CCL21 antibody (AA 24-134)

Catalog No. ABIN732698

Product Details anti-CCL21 Antibody

Target: CCL21 (Chemokine (C-C Motif) Ligand 21 (CCL21))

Binding Specificity: AA 24-134

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CCL21 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Cross-Reactivity: Mouse, Rat

Predicted Reactivity: Human,Dog,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human CCL21

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

References for anti-CCL21 antibody (ABIN732698)

Borrelli, Abrão, Taube, Darb-Esfahani, Köhler, Kaufmann, Chiantera, Mechsner: "Immunohistochemical Investigation of Metastasis-Related Chemokines in Deep-Infiltrating Endometriosis and Compromised Pelvic Sentinel Lymph Nodes." in: Reproductive sciences (Thousand Oaks, Calif.), (2015) (PubMed).

Target Details for CCL21

Target: CCL21 (Chemokine (C-C Motif) Ligand 21 (CCL21))

Alternative Name: CCL21/6Ckine (CCL21 Products)

Synonyms: 6Ckine antibody, CKb9 antibody, ECL antibody, SCYA21 antibody, SLC antibody, TCA4 antibody, ccl21 antibody, Ccl21b antibody, C-C motif chemokine ligand 21 antibody, C-C motif chemokine 21 antibody, CCL21 antibody, ccl21 antibody, Ccl21 antibody

Background:

Synonyms: ECL, SLC, CKb9, TCA4, 6Ckine, SCYA21, C-C motif chemokine 21, Beta-chemokine exodus-2, Secondary lymphoid-tissue chemokine, Small-inducible cytokine A21, CCL21, UNQ784/PRO1600

Background: Inhibits hemopoiesis and stimulates chemotaxis. Chemotactic in vitro for thymocytes and activated T-cells, but not for B-cells, macrophages, or neutrophils. Shows preferential activity towards naive T-cells. May play a role in mediating homing of lymphocytes to secondary lymphoid organs. Binds to atypical chemokine receptor ACKR4 and mediates the recruitment of beta-arrestin (ARRB1/2) to ACKR4.

Gene ID: 6366

UniProt: O00585

Pathways: Regulation of Actin Filament Polymerization