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NeuN antibody (AA 51-150)

RBFOX3 Reactivity: Human, Mouse, Rat, Rabbit WB, ELISA, FACS, IF (cc), IF (p), IHC (p), IHC (fro) Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN732068
  • Target See all NeuN (RBFOX3) Antibodies
    NeuN (RBFOX3) (RNA Binding Protein, Fox-1 Homolog 3 (RBFOX3))
    Binding Specificity
    • 15
    • 5
    • 5
    • 4
    • 1
    • 1
    • 1
    • 1
    AA 51-150
    Reactivity
    • 57
    • 47
    • 42
    • 15
    • 4
    • 3
    • 1
    • 1
    • 1
    Human, Mouse, Rat, Rabbit
    Host
    • 44
    • 15
    • 3
    Rabbit
    Clonality
    • 36
    • 26
    Polyclonal
    Conjugate
    • 25
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This NeuN antibody is un-conjugated
    Application
    • 33
    • 18
    • 17
    • 13
    • 13
    • 12
    • 12
    • 10
    • 5
    • 4
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Cross-Reactivity
    Human, Mouse, Rabbit, Rat
    Predicted Reactivity
    Dog,Cow,Horse
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human NeuN
    Isotype
    IgG
    Top Product
    Discover our top product RBFOX3 Primary Antibody
  • Application Notes
    WB 1:300-5000
    ELISA 1:500-1000
    FCM 1:20-100
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Expiry Date
    12 months
  • Kopec, Rivera, Lacagnina, Hanamsagar, Bilbo: "Optimized solubilization of TRIzol-precipitated protein permits Western blotting analysis to maximize data available from brain tissue." in: Journal of neuroscience methods, Vol. 280, pp. 64-76, (2017) (PubMed).

    Wang, Tian, Wang, Wei, Wu, Wang, Wang, Yang, Ji, Li: "Anti-inflammatory and retinal protective effects of capsaicin on ischaemia-induced injuries through the release of endogenous somatostatin." in: Clinical and experimental pharmacology & physiology, Vol. 44, Issue 7, pp. 803-814, (2017) (PubMed).

    Ridder, Sevko, Heide, Dams, Rupp, Macas, Starmann, Tjwa, Plate, Sültmann, Altevogt, Umansky, Momma: "Extracellular vesicle-mediated transfer of functional RNA in the tumor microenvironment." in: Oncoimmunology, Vol. 4, Issue 6, pp. e1008371, (2015) (PubMed).

    Fontes, Ramsey, Polk, Koop, Denisova, Belousov: "Death of Neurons following Injury Requires Conductive Neuronal Gap Junction Channels but Not a Specific Connexin." in: PLoS ONE, Vol. 10, Issue 5, pp. e0125395, (2015) (PubMed).

    Hu, Lin, Zhu, Li, Chen: "Anti-inflammatory effects of Gualou Guizhi decoction in transient focal cerebral ischemic brains. [Corrected]." in: Molecular medicine reports, Vol. 12, Issue 3, pp. 3998, (2015) (PubMed).

    Guo, Zhang, Xu, Zhi, Han, Zhou, Liu, Lin, Zhang: "Bone marrow-derived, neural-like cells have the characteristics of neurons to protect the peripheral nerve in microenvironment." in: Stem cells international, Vol. 2015, pp. 941625, (2015) (PubMed).

    Zhao, Dumanis, Tamboli, Rodriguez, Jo Ladu, Moussa, William Rebeck: "Human APOE genotype affects intraneuronal A?1-42 accumulation in a lentiviral gene transfer model." in: Human molecular genetics, Vol. 23, Issue 5, pp. 1365-75, (2014) (PubMed).

    Zhao, Zhang, Davis, Rebeck: "Aging reduces glial uptake and promotes extracellular accumulation of A? from a lentiviral vector." in: Frontiers in aging neuroscience, Vol. 6, pp. 210, (2014) (PubMed).

    Yu, Chen, Wang, Kuang, Liu, Zhang, Du: "Neuroprotective effect of kaempferol glycosides against brain injury and neuroinflammation by inhibiting the activation of NF-?B and STAT3 in transient focal stroke." in: PLoS ONE, Vol. 8, Issue 2, pp. e55839, (2013) (PubMed).

    Li, Liang, Guan, Fan, Chi, Yang: "Regular treadmill running improves spatial learning and memory performance in young mice through increased hippocampal neurogenesis and decreased stress." in: Brain research, Vol. 1531, pp. 1-8, (2013) (PubMed).

    Wei, Chen, Chen, Lai, Liu, Deng, Zhou, Zhang, Li, Lii, Liu, Wang, Nie: "β-Asarone inhibits neuronal apoptosis via the CaMKII/CREB/Bcl-2 signaling pathway in an in vitro model and AβPP/PS1 mice." in: Journal of Alzheimer's disease : JAD, Vol. 33, Issue 3, pp. 863-80, (2013) (PubMed).

    Zhao, Zhang, Wang, Chen, Ji, Zhang: "(S)-ZJM-289, a nitric oxide-releasing derivative of 3-n-butylphthalide, protects against ischemic neuronal injury by attenuating mitochondrial dysfunction and associated cell death." in: Neurochemistry international, Vol. 60, Issue 2, pp. 134-44, (2012) (PubMed).

    Jiang, Fu, Tian, Zhu, Hou: "Curculigoside A attenuates experimental cerebral ischemia injury in vitro and vivo." in: Neuroscience, Vol. 192, pp. 572-9, (2011) (PubMed).

    Jiang, Tian, Fu, Zhu, Hou: "Neuroprotective efficacy and therapeutic window of Forsythoside B: in a rat model of cerebral ischemia and reperfusion injury." in: European journal of pharmacology, Vol. 640, Issue 1-3, pp. 75-81, (2010) (PubMed).

  • Target
    NeuN (RBFOX3) (RNA Binding Protein, Fox-1 Homolog 3 (RBFOX3))
    Alternative Name
    FOX3/NeuN (RBFOX3 Products)
    Synonyms
    FOX-3 antibody, FOX3 antibody, HRNBP3 antibody, NEUN antibody, Fox-3 antibody, Hrnbp3 antibody, NeuN antibody, Neuna60 antibody, Neun antibody, RGD1560070 antibody, RNA binding fox-1 homolog 3 antibody, RNA binding protein, fox-1 homolog (C. elegans) 3 antibody, RNA binding protein, fox-1 homolog 3 antibody, RBFOX3 antibody, Rbfox3 antibody
    Background

    Synonyms: FOX3, NEUN, FOX-3, HRNBP3, RNA binding protein fox-1 homolog 3, Fox-1 homolog C, RBFOX3

    Background: Vertebrate neuron-specific nuclear protein called NeuN (Neuronal Nuclei) is an excellent marker for neurons in primary cultures and in retinoic acid-stimulated P19 cells. It is also useful for identifying neurons in transplants. NeuN is a neuron-specific, DNA-binding nuclear protein in vertebrates. In mice, NeuN is observed in most neuronal cell types throughout the nervous system, including cerebellum, cerebral cortex, hippocampus, thalamus and spinal cord, as well as the dorsal root ganglia, sympathetic chain ganglia and enteric ganglia of the peripheral nervous system. NeuN immunoreactivity is first observed in neurons when they become post-mitotic and are initiating cellular and morphological differentiation. No staining is observed in proliferative zones. NeuN has been used as an immunohistochemical marker for excitotoxic lesions of the brain as well as in the diagnosis of a wide range of human tissue specimens from the central and peripheral nervous systems.

    Gene ID
    146713
    UniProt
    A6NFN3
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