SFTPD antibody (AA 301-375)

Catalog No. ABIN731678

Product Details anti-SFTPD Antibody

Target: SFTPD (Surfactant Protein D (SFTPD))

Binding Specificity: AA 301-375

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SFTPD antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Cross-Reactivity: Human, Mouse, Rat

Predicted Reactivity: Dog

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human SP-D

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

References for anti-SFTPD antibody (ABIN731678)

Chen, Liu, Lu, Zhu, Tang, Wang, Lu: "Functional roles of C/EBPα and SUMO‑modification in lung development." in: International journal of molecular medicine, Vol. 40, Issue 4, pp. 1037-1046, (2018) (PubMed).

Furukawa, Nagaike, Ozaki: "Databases for technical aspects of immunohistochemistry." in: Journal of toxicologic pathology, Vol. 30, Issue 1, pp. 79-107, (2017) (PubMed).

Ferretti, Fortwendel, Gebb, Barrington: "Autoantibody-Mediated Pulmonary Alveolar Proteinosis in Rasgrp1-Deficient Mice." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 197, Issue 2, pp. 470-9, (2016) (PubMed).

Sung, Liang, Lee, Yen, Hsiao, Wang, Jiang-Shieh, Tsai, Chen: "The protective effect of eupafolin against TNF-?-induced lung inflammation via the reduction of intercellular cell adhesion molecule-1 expression." in: Journal of ethnopharmacology, Vol. 170, pp. 136-47, (2015) (PubMed).

Target Details for SFTPD

Target: SFTPD (Surfactant Protein D (SFTPD))

Alternative Name: SP-D/PSPD (SFTPD Products)

Synonyms: COLEC7 antibody, PSP-D antibody, SFTP4 antibody, SP-D antibody, BDE antibody, BDSD antibody, HOX4I antibody, SPD antibody, AI573415 antibody, Sftp4 antibody, surfactant protein D antibody, homeobox D13 antibody, surfactant associated protein D antibody, SFTPD antibody, HOXD13 antibody, Sftpd antibody, SP-D antibody

Background:

Synonyms: SP-D, PSP-D, SFTP4, COLEC7, Pulmonary surfactant-associated protein D, Collectin-7, Lung surfactant protein D, SFTPD, PSPD

Background: Contributes to the lung's defense against inhaled microorganisms, organic antigens and toxins. Interacts with compounds such as bacterial lipopolysaccharides, oligosaccharides and fatty acids and modulates leukocyte action in immune response. May participate in the extracellular reorganization or turnover of pulmonary surfactant. Binds strongly maltose residues and to a lesser extent other alpha-glucosyl moieties.

Gene ID: 6441

UniProt: P35247