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HBSAg antibody (Cy3)

HBsAg Reactivity: Virus, Human, Mouse WB, IF (p), IF (cc) Host: Goat Polyclonal Cy3
Catalog No. ABIN731306
  • Target See all HBSAg (HBsAg) Antibodies
    HBSAg (HBsAg) (Hepatitis B Virus Surface Antigen (HBsAg))
    Reactivity
    • 98
    • 23
    • 20
    • 17
    • 3
    • 1
    • 1
    Virus, Human, Mouse
    Host
    • 60
    • 35
    • 27
    • 2
    Goat
    Clonality
    • 60
    • 57
    Polyclonal
    Conjugate
    • 75
    • 15
    • 13
    • 11
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This HBSAg antibody is conjugated to Cy3
    Application
    • 75
    • 36
    • 21
    • 13
    • 12
    • 12
    • 12
    • 10
    • 6
    • 6
    • 6
    • 6
    • 5
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc))
    Cross-Reactivity
    Human, Mouse, Virus
    Predicted Reactivity
    Bee
    Purification
    Purified by Protein A.
    Immunogen
    Human Hepatitis B Surface Antigen
    Isotype
    IgG
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    Discover our top product HBsAg Primary Antibody
  • Application Notes
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Expiry Date
    12 months
  • Target
    HBSAg (HBsAg) (Hepatitis B Virus Surface Antigen (HBsAg))
    Alternative Name
    Hbsag (HBsAg Products)
    Target Type
    Viral Protein
    Background

    Synonyms: HBsAg, HBV major surface antigen, HBV surface antigen, Hepatitis B Virus major surface antigen, Major surface antigen, S, Human Hepatitis B Surface Antigen

    Background: Hepatitis B Virus (HBV) infection induces a disease state characterised by liver damage, inflammation and viral persistence. Infection also increases the risk of hepatocellular carcinoma. HBV belongs to the Hepadnaviridae family of viruses. Its genome consists of partially double stranded circular DNA. The DNA is enclosed in a nucleocapsid, or core antigen (HBcAg), which is surrounded by a spherical envelope (surface antigen or HBsAg). The core antigen shares its sequences with the e antigen (HBeAg) but no cross reactivity between the two proteins has been observed. The HBV genome also encodes a DNA polymerase that also acts as a reverse transcriptase. Hepatitis B infection is normally diagnosed from serological tests that detect HBsAg but as the disease progresses this antigen may no longer be present in the blood and tests for HBcAg are used. If HBsAg can be detected in the blood for longer than six months, chronic hepatitis B is diagnosed. The antigenic determinant of the protein moiety of the HBsAg determines specific characteristics of different serotypes and provides the basis of immunodetection. HBsAg has antigenic heterogeneity, specifically, two pairs of sub specific determinants, d/y and w/r allow the following combinations: adw, ayw, adr, ayr.

    UniProt
    Q67926
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