Dopamine d2 Receptor antibody (AA 201-300)

Catalog No. ABIN730858

Product Details anti-Dopamine d2 Receptor Antibody

Target: Dopamine d2 Receptor (DRD2) (Dopamine Receptor D2 (DRD2))

Binding Specificity: AA 201-300

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Dopamine d2 Receptor antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Cross-Reactivity: Human, Mouse, Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human DRD2

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

References for anti-Dopamine d2 Receptor antibody (ABIN730858)

Qian, Cai, Wang, Zhang, Zhao, Qian, Yang, Liu, Hasegawa: "Effect of Gingerol on Cisplatin-Induced Pica Analogous to Emesis Via Modulating Expressions of Dopamine 2 Receptor, Dopamine Transporter and Tyrosine Hydroxylase in the Vomiting Model of Rats." in: Yonago acta medica, Vol. 59, Issue 2, pp. 100-10, (2016) (PubMed).

Yano, Hide, Uekawa, Honda, Mikami, Kuratsu: "Mixed Pituitary Gangliocytoma and Prolactinoma Resistant to the Cabergoline Treatment." in: World neurosurgery, Vol. 95, pp. 620.e17-620.e22, (2016) (PubMed).

Zhang, Zhang, Zhang, Meng, Jia, Zhang, Bu, Zhu, Ma, Ye, Zhang, Ren, Sun, Tang: "Moderate swimming suppressed the growth and metastasis of the transplanted liver cancer in mice model: with reference to nervous system." in: Oncogene, Vol. 35, Issue 31, pp. 4122-31, (2016) (PubMed).

Mao, Yu, Hu, Hu: "Dopamine D2 receptor blocker thioridazine induces cell death in human uterine cervical carcinoma cell line SiHa." in: The journal of obstetrics and gynaecology research, Vol. 41, Issue 8, pp. 1240-5, (2015) (PubMed).

Salgado, López-Doval, Pereiro, Lafuente: "Perfluorooctane sulfonate (PFOS) exposure could modify the dopaminergic system in several limbic brain regions." in: Toxicology letters, Vol. 240, Issue 1, pp. 226-35, (2015) (PubMed).

Hu, Liu, Qiao: "Increased extracellular dopamine and 5-hydroxytryptamine levels contribute to enhanced subthalamic nucleus neural activity during exhausting exercise." in: Biology of sport, Vol. 32, Issue 3, pp. 187-92, (2015) (PubMed).

Xu, Wang, Chen, Chen, Li, Shao, Li, Lu, Zhou: "Dopamine D1 receptor activation induces dehydroepiandrosterone sulfotransferase (SULT2A1) in HepG2 cells." in: Acta pharmacologica Sinica, Vol. 35, Issue 7, pp. 889-98, (2014) (PubMed).

Target Details for Dopamine d2 Receptor

Target: Dopamine d2 Receptor (DRD2) (Dopamine Receptor D2 (DRD2))

Alternative Name: DRD2 (DRD2 Products)

Background:

Synonyms: D2R, D2DR, D(2) dopamine receptor, Dopamine D2 receptor, DRD2

Background: Dopamine receptor whose activity is mediated by G proteins which inhibit adenylyl cyclase.

Gene ID: 1813

UniProt: P14416

Pathways: Positive Regulation of Peptide Hormone Secretion, Negative Regulation of Hormone Secretion, cAMP Metabolic Process, Inositol Metabolic Process, Regulation of G-Protein Coupled Receptor Protein Signaling, Feeding Behaviour, Negative Regulation of Transporter Activity, Regulation of long-term Neuronal Synaptic Plasticity