Melatonin Receptor 1B antibody (AA 201-300)

Catalog No. ABIN730318

Product Details anti-Melatonin Receptor 1B Antibody

Target: Melatonin Receptor 1B (MTNR1B)

Binding Specificity: AA 201-300

Reactivity: Human, Mouse, Rat, Goat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Melatonin Receptor 1B antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Cross-Reactivity: Goat, Human, Mouse, Rat

Predicted Reactivity: Dog

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human MTNR1B

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

References for anti-Melatonin Receptor 1B antibody (ABIN730318)

Jang, Na, Hong, Lee, Moon, Cho, Park, Lee, Chang, Lee, Ko, Lee, Choi: "Synergistic effect of melatonin and ghrelin in preventing cisplatin-induced ovarian damage via regulation of FOXO3a phosphorylation and binding to the p27Kip1promoter in primordial follicles." in: Journal of pineal research, Vol. 63, Issue 3, (2017) (PubMed).

Brockus, Hart, Gilfeather, Fleming, Lemley: "Dietary melatonin alters uterine artery hemodynamics in pregnant Holstein heifers." in: Domestic animal endocrinology, Vol. 55, pp. 1-10, (2016) (PubMed).

Wang, Liu, Wu, Ma, Ahmad, Liu, Han, Jiang, Zhang, Yang: "Melatonin suppresses apoptosis and stimulates progesterone production by bovine granulosa cells via its receptors (MT1 and MT2)." in: Theriogenology, Vol. 78, Issue 7, pp. 1517-26, (2012) (PubMed).

Target Details for Melatonin Receptor 1B

Target: Melatonin Receptor 1B (MTNR1B)

Alternative Name: MTNR1B (MTNR1B Products)

Synonyms: FGQTL2 antibody, MEL-1B-R antibody, MT2 antibody, Mel1b-r antibody, Mel-1B-R antibody, MTNR1B antibody, mtnr1br antibody, MEL1B antibody, Mel1b antibody, Mt2 antibody, mel1b antibody, mtnr1b antibody, melatonin receptor 1B antibody, melatonin receptor type 1C S homeolog antibody, melatonin receptor type 1Ba antibody, MTNR1B antibody, Mtnr1b antibody, mtnr1c.S antibody, mtnr1bb antibody, mtnr1ba antibody

Background:

Synonyms: MT2, FGQTL2, MEL-1B-R, Melatonin receptor type 1B, Mel1b receptor, MTNR1B

Background: High affinity receptor for melatonin. Likely to mediates the reproductive and circadian actions of melatonin. The activity of this receptor is mediated by pertussis toxin sensitive G proteins that inhibit adenylate cyclase activity.

Gene ID: 4544

UniProt: P49286