ZBTB7A antibody (AA 151-250)

Catalog No. ABIN729448

Product Details anti-ZBTB7A Antibody

Target: ZBTB7A (Zinc Finger and BTB Domain Containing 7A (ZBTB7A))

Binding Specificity: AA 151-250

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ZBTB7A antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Cross-Reactivity: Human

Predicted Reactivity: Mouse,Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Pokemon

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

References for anti-ZBTB7A antibody (ABIN729448)

Zhao, Yao, Li, An, Chen, Sun, Kang, Wang, Hu: "Pokemon enhances proliferation, cell cycle progression and anti-apoptosis activity of colorectal cancer independently of p14(ARF)-MDM2-p53 pathway." in: Medical oncology (Northwood, London, England), Vol. 31, Issue 12, pp. 288, (2014) (PubMed).

Target Details for ZBTB7A

Target: ZBTB7A (Zinc Finger and BTB Domain Containing 7A (ZBTB7A))

Alternative Name: Pokemon (ZBTB7A Products)

Synonyms: ZBTB7A antibody, FBI-1 antibody, FBI1 antibody, LRF antibody, ZBTB7 antibody, ZNF857A antibody, pokemon antibody, 9030619K07Rik antibody, 9130006G12Rik antibody, AI452336 antibody, Lrf antibody, Pokemon antibody, Zbtb7 antibody, OCZF antibody, zinc finger and BTB domain containing 7A antibody, zinc finger and BTB domain containing 7C antibody, zinc finger and BTB domain containing 7a antibody, ZBTB7A antibody, ZBTB7C antibody, Zbtb7a antibody

Background:

Synonyms: LRF, FBI1, FBI-1, ZBTB7, ZNF857A, pokemon, Zinc finger and BTB domain-containing protein 7A, Factor binding IST protein 1, Factor that binds to inducer of short transcripts protein 1, HIV-1 1st-binding protein 1, Leukemia/lymphoma-related factor, POZ and Krueppel erythroid myeloid ontogenic factor, POK erythroid myeloid ontogenic factor, TTF-I-interacting peptide 21, TIP21, Zinc finger protein 857A, ZBTB7A

Background: Plays a key role in the instruction of early lymphoid progenitors to develop into B lineage by repressing T-cell instructive Notch signals (By similarity). Specifically represses the transcription of the CDKN2A gene. Efficiently abrogates E2F1-dependent CDKN2A transactivation/de-repression. Binds to the consensus sequence 5'-[GA][CA]GACCCCCCCCC-3' (By similarity).

Gene ID: 51341

UniProt: O95365