S100A1 antibody

Catalog No. ABIN728983

Product Details anti-S100A1 Antibody

Target: S100A1 (S100 Calcium Binding Protein A1 (S100A1))

Reactivity: Human, Mouse, Rat, Cow, Chicken, Dog

Host: Rabbit

Clonality: Polyclonal

Conjugate: This S100A1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Cross-Reactivity: Chicken, Cow, Dog, Human, Mouse, Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human S100A1

Isotype: IgG

Application Details

Application Notes: WB(1:100-500)
Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for S100A1

Target: S100A1 (S100 Calcium Binding Protein A1 (S100A1))

Alternative Name: S-100/S100A1 (S100A1 Products)

Synonyms: S100 antibody, S100-alpha antibody, S100A antibody, S100A1 antibody, DKFZp468K0511 antibody, AI266795 antibody, S100a antibody, S100 calcium binding protein A1 antibody, S100A1 antibody, S100a1 antibody, s100a1 antibody

Background:

Synonyms: S-100 protein alpha subunit, S-100 protein alpha chain, Protein S100-A1, S100 calcium-binding protein A1, S100 alpha, Protein S100-A1, S-100 protein alpha chain, S-100 protein subunit alpha, S100, S100 Calcium Binding Protein A1, S100 calcium-binding protein A1, S100 protein alpha polypeptide, S100A, S100A1, S10A1_HUMAN.

Background: S-100 is group of solubilities, the relatively low molecular mass, the high acidic protein, is the neuroglia cell specificity protein, may also exist in the nerve fiber. In the research intestines nervous system's shape characteristic and the structural feature, S-100 has the good expressive function. The S-100 protein its physiological action was not still clear, possible and in the cell the calcium ion medium's control action concerns. The S-100 protein may exist in the neurinoma, becomes the cartilage cytoma, the chondrosarcoma, the osteosarcoma, the neuroglia lump, Lang Gehan the Si cytoma, some cancers and the melanocyte cell tumor and so on. In the immunity group, damages except the malignant melanoma skin, the S-100 protein also increases in the benign melanocyte cell mole, for example: The blue nevus, the ordinary day after tomorrow mole, the freckle type mole, the Spitz mole, the gas globuli cell mole, the pigment spindle-shaped cell mole and in the maldevelopment mole will express. Also has reported that the S-100 protein's dyeing intensity and tumour cell's melanocyte content assumes the inverse correlation. The knot contracts the organization proliferative or kisses the nerve the melanoma undyeable color. SUBUNIT: Dimer of either two alpha chains, or two beta chains, or one alpha and one beta chain.

Molecular Weight: 10kDa

Gene ID: 6271

Pathways: Regulation of Muscle Cell Differentiation, Toll-Like Receptors Cascades, S100 Proteins