MICA antibody (AA 120-170)
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- Target See all MICA Antibodies
- MICA (MHC Class I Polypeptide-Related Sequence A (MICA))
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Binding Specificity
- AA 120-170
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This MICA antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Cross-Reactivity
- Human
- Purification
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human MICA
- Isotype
- IgG
- Top Product
- Discover our top product MICA Primary Antibody
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- Application Notes
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WB 1:100-1000
IHC-P 1:100-500
IF(IHC-P) 1:50-200 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C for 12 months.
- Expiry Date
- 12 months
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Scorpion venom activates natural killer cells in hepatocellular carcinoma via the NKG2D-MICA pathway." in: International immunopharmacology, Vol. 35, pp. 307-14, (2016) (PubMed).
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Scorpion venom activates natural killer cells in hepatocellular carcinoma via the NKG2D-MICA pathway." in: International immunopharmacology, Vol. 35, pp. 307-14, (2016) (PubMed).
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- Target
- MICA (MHC Class I Polypeptide-Related Sequence A (MICA))
- Alternative Name
- MICA (MICA Products)
- Synonyms
- MIC-A antibody, PERB11.1 antibody, MHC class I polypeptide-related sequence A antibody, MICA antibody
- Background
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Synonyms: MIC-A, PERB11.1, MHC class I polypeptide-related sequence A, MICA
Background: Seems to have no role in antigen presentation. Acts as a stress-induced self-antigen that is recognized by gamma delta T-cells. Ligand for the KLRK1/NKG2D receptor. Binding to KLRK1 leads to cell lysis.
- Gene ID
- 100507436
- UniProt
- Q29983
- Pathways
- Activation of Innate immune Response, Transition Metal Ion Homeostasis, Human Leukocyte Antigen (HLA) in Adaptive Immune Response
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