IFNB1 antibody (AA 101-187)

Catalog No. ABIN728158

Product Details anti-IFNB1 Antibody

Target: IFNB1 (Interferon, beta 1, Fibroblast (IFNB1))

Binding Specificity: AA 101-187

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IFNB1 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Cross-Reactivity: Human, Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human IFN-beta

Isotype: IgG

Application Details

Application Notes: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

References for anti-IFNB1 antibody (ABIN728158)

Quek, Luff, Cheung, Kozlov, Gatei, Lee, Bellingham, Noakes, Lim, Barnett, Dingwall, Wolvetang, Mashimo, Roberts, Lavin: "Rats with a missense mutation in Atm display neuroinflammation and neurodegeneration subsequent to accumulation of cytosolic DNA following unrepaired DNA damage." in: Journal of leukocyte biology, Vol. 101, Issue 4, pp. 927-947, (2016) (PubMed).

Target Details for IFNB1

Target: IFNB1 (Interferon, beta 1, Fibroblast (IFNB1))

Alternative Name: IFN-beta (IFNB1 Products)

Synonyms: IFB antibody, IFF antibody, IFNB antibody, IFN-beta antibody, Ifb antibody, Ifnb antibody, IFNb antibody, interferon beta 1 antibody, interferon beta 1, fibroblast antibody, interferon, beta 1, fibroblast antibody, IFNB1 antibody, Ifnb1 antibody

Background:

Synonyms: IFB, IFF, IFNB, IFN-beta, Interferon beta, Fibroblast interferon, IFNB1

Background: Has antiviral, antibacterial and anticancer activities.

Gene ID: 3456

UniProt: P01574

Pathways: JAK-STAT Signaling, TCR Signaling, TLR Signaling, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity, Hepatitis C, Autophagy, Inflammasome