Factor VIII antibody (AA 1451-1550)

Catalog No. ABIN728000

Product Details anti-Factor VIII Antibody

Target: Factor VIII (F8) (Coagulation Factor VIII (F8))

Binding Specificity: AA 1451-1550

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Factor VIII antibody is un-conjugated

Application: ELISA, Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Cross-Reactivity: Human, Mouse

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human factor VIII

Isotype: IgG

Application Details

Application Notes: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

References for anti-Factor VIII antibody (ABIN728000)

Hu, Zhou, Gao, Liu, Yan, Zou, Chen: "IFN-? inhibits osteopontin expression in human decidual stromal cells and can be attenuated by 1?,25-dihydroxyvitamin D3." in: American journal of reproductive immunology (New York, N.Y. : 1989), Vol. 68, Issue 4, pp. 353-61, (2012) (PubMed).

Hu, Song, He, Freeman, Parish, Yuan, Yu, Tang: "Heparanase and vascular endothelial growth factor expression is increased in hypoxia-induced retinal neovascularization." in: Investigative ophthalmology & visual science, Vol. 53, Issue 11, pp. 6810-7, (2012) (PubMed).

Li, Ye, Guo, Yang: "Suppression of bladder cancer cell tumorigenicity in an athymic mouse model by adenoviral vector-mediated transfer of LRIG1." in: Oncology reports, Vol. 26, Issue 2, pp. 439-46, (2011) (PubMed).

Zhou, Zhu, Zou, Wang: "Changes in number and biological function of endothelial progenitor cells in hypertension disorder complicating pregnancy." in: Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban, Vol. 28, Issue 6, pp. 670-3, (2008) (PubMed).

Target Details for Factor VIII

Target: Factor VIII (F8) (Coagulation Factor VIII (F8))

Alternative Name: factor 8/F8 (F8 Products)

Synonyms: fb61d02 antibody, wu:fb61d02 antibody, Cf-8 antibody, Cf8 antibody, FVIII antibody, AHF antibody, DXS1253E antibody, F8B antibody, F8C antibody, HEMA antibody, coagulation factor VIIi antibody, coagulation factor VIII antibody, coagulation factor VIII, procoagulant component antibody, f7i antibody, F8 antibody

Background:

Synonyms: AHF, F8B, F8C, HEMA, FVIII, DXS1253E, Coagulation factor VIII, Antihemophilic factor, Procoagulant component, F8

Background: Factor VIII, along with calcium and phospholipid, acts as a cofactor for factor IXa when it converts factor X to the activated form, factor Xa.

Gene ID: 2157

UniProt: P00451