Factor VIII antibody (AA 1451-1550)

Catalog No. ABIN728000

Product Details anti-Factor VIII Antibody

Target: Factor VIII (F8) (Coagulation Factor VIII (F8))

Binding Specificity: AA 1451-1550

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Factor VIII antibody is un-conjugated

Application: ELISA, Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Cross-Reactivity: Human, Mouse

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human factor VIII

Isotype: IgG

Application Details

Application Notes: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

References for anti-Factor VIII antibody (ABIN728000)

Hu, Zhou, Gao, Liu, Yan, Zou, Chen: "IFN-? inhibits osteopontin expression in human decidual stromal cells and can be attenuated by 1?,25-dihydroxyvitamin D3." in: American journal of reproductive immunology (New York, N.Y. : 1989), Vol. 68, Issue 4, pp. 353-61, (2012) (PubMed).

Hu, Song, He, Freeman, Parish, Yuan, Yu, Tang: "Heparanase and vascular endothelial growth factor expression is increased in hypoxia-induced retinal neovascularization." in: Investigative ophthalmology & visual science, Vol. 53, Issue 11, pp. 6810-7, (2012) (PubMed).

Li, Ye, Guo, Yang: "Suppression of bladder cancer cell tumorigenicity in an athymic mouse model by adenoviral vector-mediated transfer of LRIG1." in: Oncology reports, Vol. 26, Issue 2, pp. 439-46, (2011) (PubMed).

Zhou, Zhu, Zou, Wang: "Changes in number and biological function of endothelial progenitor cells in hypertension disorder complicating pregnancy." in: Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban, Vol. 28, Issue 6, pp. 670-3, (2008) (PubMed).

Target Details for Factor VIII

Target: Factor VIII (F8) (Coagulation Factor VIII (F8))

Alternative Name: factor 8/F8 (F8 Products)

Background:

Synonyms: AHF, F8B, F8C, HEMA, FVIII, DXS1253E, Coagulation factor VIII, Antihemophilic factor, Procoagulant component, F8

Background: Factor VIII, along with calcium and phospholipid, acts as a cofactor for factor IXa when it converts factor X to the activated form, factor Xa.

Gene ID: 2157

UniProt: P00451