RRAD antibody (AA 211-308)

Catalog No. ABIN727190

Product Details anti-RRAD Antibody

Target: RRAD (Ras-Related Associated with Diabetes (RRAD))

Binding Specificity: AA 211-308

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RRAD antibody is un-conjugated

Application: ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Predicted Reactivity: Human,Mouse,Rat,Dog,Cow,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human RRAD

Isotype: IgG

Application Details

Application Notes: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for RRAD

Target: RRAD (Ras-Related Associated with Diabetes (RRAD))

Alternative Name: RRAD (RRAD Products)

Synonyms: ZGC:63471 antibody, RRAD antibody, RAD antibody, RAD1 antibody, REM3 antibody, Rad antibody, RRAD, Ras related glycolysis inhibitor and calcium channel regulator antibody, Ras-related associated with diabetes antibody, RRAD antibody, Rrad antibody

Background:

Synonyms: RAD, Ras-related associated with diabetes, RAD1, REM3, Cell cycle checkpoint protein Hrad1, Cell cycle checkpoint protein Rad 1 A / B, Cell cycle checkpoint protein RAD1, Checkpoint control protein HRAD1, Checkpoint control protein RAD1, DNA repair exonuclease, DNA repair exonuclease rad1, DNA repair exonuclease rad1 homolog, DNA repair exonuclease REC1, DNA repair protein RAD1, EC 3.1.11.2, Exonuclease homolog RAD1, GTP-binding protein RAD, hRAD 1, hRAD1, MGC77779, RAD 1, RAD, RAD1 homolog S. pombe, RAD1 homolog, Rad1 like DNA damage checkpoint, Rad1 like DNA damage checkpoint protein, RAD1, S. pombe, homolog of, Ras associated with diabetes, REC 1, REC1, RRAD, RAD_HUMAN.

Background: Human Rad1 is a component of a heterotrimeric PCNA like complex that also contains the Rad9 and Hus1 proteins. This complex is believed to be involved in cellular responses to DNA damage, possibly by associating with Rad17 and several components of the PCNA-loading heteropentamer, replication factor C. Human Rad1 exhibits significant homology to Rad1 from S. pombe, and its expression in yeast rad1 mutants has been shown to partially restore radiation resistance and G2 checkpoint activity. It has also been shown to possess exonuclease activity.

Gene ID: 6236