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PMP22 antibody (AA 101-160) (Biotin)

PMP22 Reactivity: Rat, Mouse WB, ELISA, IHC (p), IHC (fro) Host: Rabbit Polyclonal Biotin
Catalog No. ABIN726682
  • Target See all PMP22 Antibodies
    PMP22 (Peripheral Myelin Protein 22 (PMP22))
    Binding Specificity
    • 14
    • 7
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 101-160
    Reactivity
    • 47
    • 40
    • 31
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Rat, Mouse
    Host
    • 58
    • 6
    Rabbit
    Clonality
    • 50
    • 14
    Polyclonal
    Conjugate
    • 25
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This PMP22 antibody is conjugated to Biotin
    Application
    • 45
    • 19
    • 14
    • 14
    • 12
    • 7
    • 6
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Cross-Reactivity
    Mouse, Rat
    Predicted Reactivity
    Human
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human PMP-22
    Isotype
    IgG
    Top Product
    Discover our top product PMP22 Primary Antibody
  • Application Notes
    WB 1:300-5000
    IHC-P 1:200-400
    IHC-F 1:100-500
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C for 12 months.
    Expiry Date
    12 months
  • Target
    PMP22 (Peripheral Myelin Protein 22 (PMP22))
    Alternative Name
    PMP22 (PMP22 Products)
    Synonyms
    CMT1A antibody, CMT1E antibody, DSS antibody, GAS-3 antibody, HMSNIA antibody, HNPP antibody, Sp110 antibody, 22kDa antibody, Gas-3 antibody, Tr antibody, trembler antibody, pmp22 antibody, wu:fa04d03 antibody, wu:fa08d03 antibody, MGC80653 antibody, PMP22 antibody, MGC69407 antibody, id:ibd2630 antibody, wu:fb81f09 antibody, zgc:136919 antibody, peripheral myelin protein 22 antibody, peripheral myelin protein 22a antibody, peripheral myelin protein 22 S homeolog antibody, peripheral myelin protein 22b antibody, PMP22 antibody, Pmp22 antibody, pmp22a antibody, pmp22.S antibody, pmp22 antibody, pmp22b antibody
    Background

    Synonyms: DSS, HNPP, CMT1A, CMT1E, GAS-3, Sp110, HMSNIA, Peripheral myelin protein 22, PMP-22, Growth arrest-specific protein 3, PMP22, GAS3

    Background: PMP22 is a 22 kDa glycoprotein expressed in the compact myelin of the peripheral nervous system. In the peripheral nervous system, PMP 22 is produced by myelinating Schwann cells and is coexpressed with the genes for myelin basic protein (MBP) during nerve development and regeneration. Alterations in the level of this protein cause several genetic human diseases. If the protein is duplicated, patients develop Charcot Marie Tooth disease. If one copy of the gene is deleted, they suffer from the inherited tendency to pressure palsies.

    Gene ID
    5376
    UniProt
    Q01453
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