FGF2 antibody (AA 143-250)

Catalog No. ABIN726425

Product Details anti-FGF2 Antibody

Target: FGF2 (Fibroblast Growth Factor 2 (Basic) (FGF2))

Binding Specificity: AA 143-250

Reactivity: Human, Mouse, Rat, Rabbit, Sheep

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FGF2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Cross-Reactivity: Human, Mouse, Rabbit, Rat, Sheep

Predicted Reactivity: Cow,Chicken

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from mouse FGF2

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

References for anti-FGF2 antibody (ABIN726425)

Zhang, Jiang, Chen, Hu, Yang, Liu et al.: "Silica-coated magnetic nanoparticles labeled endothelial progenitor cells alleviate ischemic myocardial injury and improve long-term cardiac function with magnetic field guidance in rats with ..." in: Journal of cellular physiology, Vol. 234, Issue 10, pp. 18544-18559, (2020) (PubMed).

Liu, Lu, Chen, Zhang, Wang, Li, Zhang: "B-cell leukemia/lymphoma 10 promotes angiogenesis in an experimental corneal neovascularization model." in: Eye (London, England), Vol. 32, Issue 7, pp. 1220-1231, (2019) (PubMed).

Peng, Zhang, Zhang, Zhao, Dong: "Expression of osteoprotegerin and receptor activator for the nuclear factor-κB ligand in XACB/LV-bFGF/MSCs transplantation for repair of rabbit femoral head defect necrosis." in: Journal of cellular biochemistry, (2018) (PubMed).

Eren, Turgut, Akin, Demir: "The Suppression of Wound Healing Response with Sirolimus and Sunitinib Following Experimental Trabeculectomy in a Rabbit Model." in: Current eye research, Vol. 41, Issue 3, pp. 367-76, (2016) (PubMed).

Shkurupy, Arkhipov, Neshchadim, Akhramenko, Troitskii: "In vitro effects of nanosized diamond particles on macrophages." in: Bulletin of experimental biology and medicine, Vol. 158, Issue 4, pp. 500-3, (2015) (PubMed).

He, Qi, Jia, Wang, Wang, Song, Fu, Li, Luo: "Tumor cell-secreted angiogenin induces angiogenic activity of endothelial cells by suppressing miR-542-3p." in: Cancer letters, Vol. 368, Issue 1, pp. 115-25, (2015) (PubMed).

Lee, Lee, Kim, Yang: "Anti-neovascular effect of chondrocyte-derived extracellular matrix on corneal alkaline burns in rabbits." in: Graefe's archive for clinical and experimental ophthalmology, Vol. 252, Issue 6, pp. 951-61, (2014) (PubMed).

Turgut, Eren, Akin, Bilir Can, Demir: "Impact of trastuzumab on wound healing in experimental glaucoma surgery." in: Clinical & experimental ophthalmology, (2014) (PubMed).

Turgut, Eren, Ak?n, Demir, Kobat: "Topical infliximab for the suppression of wound healing following experimental glaucoma filtration surgery." in: Drug design, development and therapy, Vol. 8, pp. 421-9, (2014) (PubMed).

Sun, Pan, Shi, Zhang, Zhang, Ye, Liu, Zhang, Zhong, Yuan: "Structural integrity, immunogenicity and biomechanical evaluation of rabbit decelluarized tracheal matrix." in: Journal of biomedical materials research. Part A, (2014) (PubMed).

Wang, Gao, Xiong, Hu, Liu, He: "VEGF and BFGF Expression and Histological Characteristics of the Bone-Tendon Junction during Acute Injury Healing." in: Journal of sports science & medicine, Vol. 13, Issue 1, pp. 15-21, (2014) (PubMed).

Chen, Wang, Chen, Ma: "Altered TGF-?2 and bFGF expression in scleral desmocytes from an experimentally-induced myopia guinea pig model." in: Graefe's archive for clinical and experimental ophthalmology, Vol. 251, Issue 4, pp. 1133-44, (2013) (PubMed).

Pan, Wang, Xiang, Shao: "Delta-like 1 serves as a new target and contributor to liver fibrosis down-regulated by mesenchymal stem cell transplantation." in: The Journal of biological chemistry, Vol. 286, Issue 14, pp. 12340-8, (2011) (PubMed).

Zhao, Cao, Liu, Xiao, Tang, Wang, Liang: "Effects of recombinant human endostatin on peritoneal angiogenesis in peritoneal dialysis rats." in: Nephrology (Carlton, Vic.), Vol. 16, Issue 6, pp. 599-606, (2011) (PubMed).

Gao, Zhao, Liang, Li, Cao, Liu: "Effect of peritoneal dialysis on expression of vascular endothelial growth factor, basic fibroblast growth factor and endostatin of the peritoneum in peritoneal dialysis patients." in: Nephrology (Carlton, Vic.), Vol. 16, Issue 8, pp. 736-42, (2011) (PubMed).

Liu, Xu, Yang, Chen, Liu, Li, Li: "Analysis of olfactory ensheathing glia transplantation-induced repair of spinal cord injury by electrophysiological, behavioral, and histochemical methods in rats." in: Journal of molecular neuroscience : MN, Vol. 41, Issue 1, pp. 25-9, (2010) (PubMed).

Target Details for FGF2

Target: FGF2 (Fibroblast Growth Factor 2 (Basic) (FGF2))

Alternative Name: bFGF (FGF2 Products)

Synonyms: BFGF antibody, FGF-2 antibody, FGFB antibody, HBGF-2 antibody, Fgf-2 antibody, Fgfb antibody, bFGF antibody, fibroblast growth factor 2 antibody, fibroblast growth factor 2 (basic) antibody, FGF2 antibody, Fgf2 antibody, fgf2 antibody

Background:

Synonyms: Fgfb, bFGF, Fgf-2, Fibroblast growth factor 2, Basic fibroblast growth factor, Heparin-binding growth factor 2, HBGF-2, Fgf2

Background: Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro (By similarity).

Gene ID: 14173

UniProt: P09038

Pathways: RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, C21-Steroid Hormone Metabolic Process, Inositol Metabolic Process, Glycosaminoglycan Metabolic Process, Protein targeting to Nucleus, S100 Proteins