GHRH antibody (AA 32-59) (Biotin)

Catalog No. ABIN726277

Product Details anti-GHRH Antibody (Biotin)

Target: GHRH (Growth Hormone Releasing Hormone (GHRH))

Binding Specificity: AA 32-59

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GHRH antibody is conjugated to Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Cross-Reactivity: Mouse, Rat

Predicted Reactivity: Human,Cow,Pig

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human GHRF

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for GHRH

Target: GHRH (Growth Hormone Releasing Hormone (GHRH))

Alternative Name: GHRH (GHRH Products)

Synonyms: GHRF antibody, GRF antibody, INN antibody, PACAP antibody, grf antibody, Ghrf antibody, growth hormone releasing hormone antibody, adenylate cyclase activating polypeptide 1 antibody, GHRH antibody, ADCYAP1 antibody, ghrh antibody, Ghrh antibody, LOC780526 antibody

Background:

Synonyms: GRF, GHRF, GHRH, Somatoliberin precursor, Somatocrinin, Sermorelin, SLIB_HUMAN.

Background: GHRF encoded by this gene belongs to the glucagon family and is a preproprotein that is produced in the hypothalamus. The preproprotein is cleaved to form a 44 aa factor, also called somatocrinin, that acts to stimulate growth hormone release from the pituitary. Variant receptors for somatocrinin have been found in several types of tumors, and antagonists of these receptors can inhibit the growth of the tumors. Defects in this gene are a cause of dwarfism, while hypersecretion of the encoded protein is a cause of gigantism.

Gene ID: 2691

Pathways: Hormone Transport, Hormone Activity, cAMP Metabolic Process