IRS3 antibody (AA 261-360) (HRP)

Catalog No. ABIN726014

Product Details anti-IRS3 Antibody (HRP)

Target: IRS3 (Insulin Receptor Substrate 3 (IRS3))

Binding Specificity: AA 261-360

Reactivity: Rat, Human, Mouse, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IRS3 antibody is conjugated to HRP

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro))

Cross-Reactivity: Human, Mouse, Pig, Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from rat IRS-3

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for IRS3

Target: IRS3 (Insulin Receptor Substrate 3 (IRS3))

Alternative Name: IRS-3 (IRS3 Products)

Synonyms: AA408304 antibody, insulin receptor substrate 3 antibody, Irs3 antibody

Background:

Synonyms: IRS1--Insulin receptor substrate-3, IRS3, IRS-3, IRS3.

Background: The family of insulin receptor substrates (IRSs) has been reported to play important roles for signal transduction of various hormones. Four members of the IRS family have been described. Each IRS is believed to have different functions, however, the distinct physiological roles of each IRS are unclear. IRS-1 may mediate the control of various cellular processes by insulin. When phosphorylated by the insulin receptor binds specifically to various cellular proteins containing SH2 domains such as phosphatidylinositol 3-kinase p85 subunit or GRB2.

Gene ID: 84021