OPRL1 antibody (AA 1-47) (Biotin)

Catalog No. ABIN725962

Product Details anti-OPRL1 Antibody (Biotin)

Target: OPRL1 (Opiate Receptor-Like 1 (OPRL1))

Binding Specificity: AA 1-47

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This OPRL1 antibody is conjugated to Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Cross-Reactivity: Human, Mouse, Rat

Predicted Reactivity: Dog,Cow,Pig,Horse,Guinea Pig

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from mouse Nociceptin receptor

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for OPRL1

Target: OPRL1 (Opiate Receptor-Like 1 (OPRL1))

Alternative Name: Nociceptin receptor (OPRL1 Products)

Synonyms: KOR-3 antibody, NOCIR antibody, OOR antibody, ORL1 antibody, KOR3 antibody, LC132 antibody, MOR-C antibody, OFQR antibody, Oprl antibody, XOR1 antibody, OPRL antibody, ORGC antibody, morc antibody, opioid related nociceptin receptor 1 antibody, opiate receptor-like 1 L homeolog antibody, opiate receptor-like 1 antibody, opioid receptor-like 1 antibody, OPRL1 antibody, oprl1.L antibody, LOC100335303 antibody, Oprl1 antibody

Background:

Synonyms: KOR3, ORGC, ORL1, Oprl, XOR1, morc, KOR-3, LC132, MOR-C, Nociceptin receptor, K3 opiate receptor, Kappa-type 3 opioid receptor, Orphanin FQ receptor, Oprl1, Oor

Background: G-protein coupled opioid receptor that functions as receptor for the endogenous neuropeptide nociceptin. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Signaling via G proteins mediates inhibition of adenylate cyclase activity and calcium channel activity. Arrestins modulate signaling via G proteins and mediate the activation of alternative signaling pathways that lead to the activation of MAP kinases. Plays a role in modulating nociception and the perception of pain. Plays a role in the regulation of locomotor activity by the neuropeptide nociceptin.

Gene ID: 18389

UniProt: P35377