NOS1 antibody (AA 51-150)

Catalog No. ABIN725585

Product Details anti-NOS1 Antibody

Target: NOS1 (Nitric Oxide Synthase 1, Neuronal (NOS1))

Binding Specificity: AA 51-150

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NOS1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Cross-Reactivity: Human, Mouse, Rat

Predicted Reactivity: Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human NOS-1

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

References for anti-NOS1 antibody (ABIN725585)

Zhu, Zhao, Luo, Li: "Gastrointestinal dysfunction in a Parkinson's disease rat model and the changes of dopaminergic, nitric oxidergic, and cholinergic neurotransmitters in myenteric plexus." in: Journal of molecular neuroscience : MN, Vol. 47, Issue 1, pp. 15-25, (2012) (PubMed).

Zhang, Liao, Ju, Song, Liu: "Neurochemical plasticity of nitric oxide synthase isoforms in neurogenic detrusor overactivity after spinal cord injury." in: Neurochemical research, Vol. 36, Issue 10, pp. 1903-9, (2011) (PubMed).

Wang, Yan, Zhao, Wu, Zhou: "The diversity of nNOS gene expression in avulsion-injured spinal motoneurons among laboratory rodents." in: Nitric oxide : biology and chemistry / official journal of the Nitric Oxide Society, Vol. 22, Issue 1, pp. 37-42, (2010) (PubMed).

Target Details for NOS1

Target: NOS1 (Nitric Oxide Synthase 1, Neuronal (NOS1))

Alternative Name: nNos (NOS1 Products)

Synonyms: NOS1 antibody, IHPS1 antibody, N-NOS antibody, NC-NOS antibody, NOS antibody, bNOS antibody, nNOS antibody, 2310005C01Rik antibody, NO antibody, NOS-I antibody, Nos-1 antibody, nos antibody, ihps1 antibody, nnos antibody, nos1 antibody, nos1-A antibody, nanos C2HC-type zinc finger 1 antibody, nitric oxide synthase 1 antibody, nitric oxide synthase 1, neuronal antibody, nitric oxide synthase 1 (neuronal) antibody, nitric oxide synthase 1 L homeolog antibody, NANOS1 antibody, NOS1 antibody, Nos1 antibody, nos1 antibody, nos1.L antibody

Background:

Synonyms: NOS, bNOS, nNOS, IHPS1, N-NOS, NC-NOS, Nitric oxide synthase, brain, Constitutive NOS, NOS type I, Neuronal NOS, Peptidyl-cysteine S-nitrosylase NOS1, NOS1

Background: Produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body. In the brain and peripheral nervous system, NO displays many properties of a neurotransmitter. Probably has nitrosylase activity and mediates cysteine S-nitrosylation of cytoplasmic target proteins such SRR.

Gene ID: 4842

UniProt: P29475

Pathways: Negative Regulation of Hormone Secretion, Myometrial Relaxation and Contraction