Secretin antibody (AA 28-54)

Catalog No. ABIN724715

Product Details anti-Secretin Antibody

Target: Secretin (SECR)

Binding Specificity: AA 28-54

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Secretin antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Cross-Reactivity: Mouse, Rat

Predicted Reactivity: Human,Pig

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Secretin

Isotype: IgG

Application Details

Application Notes: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

References for anti-Secretin antibody (ABIN724715)

Zhang, Chung, Chow: "The knockout of secretin in cerebellar Purkinje cells impairs mouse motor coordination and motor learning." in: Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, Vol. 39, Issue 6, pp. 1460-8, (2014) (PubMed).

Target Details for Secretin

Target: Secretin (SECR)

Alternative Name: Secretin (SECR Products)

Synonyms: Secr antibody, secretin antibody, SCT antibody, Sct antibody

Background:

Synonyms: SCT, Secretin precursor, SECR_HUMAN, Secr.

Background: Secretin belongs to the glucagon family. This protein is an endocrine hormone and its major site of production is the endocrine S cells located in the proximal small intestinal mucosa. The release of active secretin is stimulated by either fatty acids or an acidic pH in the duodenum. This hormone stimulates the secretion of bicarbonate-rich pancreatic fluids and has also been shown to regulate the growth and development of the stomach, small intestine, and pancreas. Secretin deficiency has been implicated in autistic syndrome, suggesting that the hormone could have a neuroendocrine function in addition to its role in digestion.

Gene ID: 6343

Pathways: Stem Cell Maintenance