NGFB antibody (AA 151-220) (Biotin)

Catalog No. ABIN724432

Product Details anti-NGFB Antibody (Biotin)

Target: NGFB (Nerve Growth Factor beta (NGFB))

Binding Specificity: AA 151-220

Reactivity: Human, Mouse, Rat, Dog

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NGFB antibody is conjugated to Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Cross-Reactivity: Dog, Human, Mouse, Rat

Predicted Reactivity: Cow,Pig,Horse,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human NGF beta

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for NGFB

Target: NGFB (Nerve Growth Factor beta (NGFB))

Alternative Name: NGF beta (NGFB Products)

Synonyms: NGFB antibody, ngfb antibody, ns:zft386 antibody, xx:zft386 antibody, zgc:109730 antibody, hsan5 antibody, beta-ngf antibody, Ngfb antibody, Beta-NGF antibody, HSAN5 antibody, beta-NGF antibody, nerve growth factor antibody, nerve growth factor b (beta polypeptide) antibody, beta-Nerve growth factor antibody, nerve growth factor (beta polypeptide) antibody, NGF antibody, ngfb antibody, FPV072 antibody, FPV076 antibody, ngf antibody, Ngf antibody

Background:

Synonyms: NGFB, HSAN5, Beta-NGF, Beta-nerve growth factor, NGF

Background: Nerve growth factor is important for the development and maintenance of the sympathetic and sensory nervous systems. Extracellular ligand for the NTRK1 and NGFR receptors, activates cellular signaling cascades through those receptor tyrosine kinase to regulate neuronal proliferation, differentiation and survival. Inhibits metalloproteinase dependent proteolysis of platelet glycoprotein VI (PubMed:20164177).

Gene ID: 4803

UniProt: P01138

Pathways: NF-kappaB Signaling, RTK Signaling, Regulation of Cell Size