beta Actin antibody (AA 1-50)

Catalog No. ABIN724340

Product Details anti-beta Actin Antibody

Key Features:

• High quality beta Actin Primary Antibody for the detection of ACTB.
• Reliable product with high standard validation data

Target: beta Actin (ACTB) (Actin, beta (ACTB))

Binding Specificity: AA 1-50

Reactivity: Human, Mouse, Rat, Rabbit, Pig, Cow

Host: Rabbit

Clonality: Polyclonal

Conjugate: This beta Actin antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Cross-Reactivity: Cow, Dog, Goat, Human, Mouse, Pig, Rabbit, Rat, Sheep, Various Species

Purification: Purified by Protein A.

Immunogen: MAP conjugated synthetic peptide derived from human beta Actin

Isotype: IgG

Product Specific Information:

What can the beta Actin Antibody ABIN724340 be used for?: This polyclonal beta Actin Antibody detects beta Actin. The beta Actin Antibody has been validated for various applications and can be used for the detection of beta Actin and derivatives by Western Blotting, ELISA, Immunohistochemistry (Paraffin-embedded Sections), Flow Cytometry, Immunofluorescence (Cultured Cells), Immunofluorescence (Paraffin-embedded Sections).

What validation data is available for this beta Actin Antibody?: The primary antibody is referenced in 254 publications and is characterized by a proven, very high reliability. It has currently 43 product images that show its performance in a variety of applications. The product is currently available in 100 μL quantity. beta Actin Antibody for the detection of beta Actin and derivatives.

What is the function of beta Actin?: This gene encodes one of six different actin proteins. Actins are highly conserved proteins that are involved in cell motility, structure, and integrity. This actin is a major constituent of the contractile apparatus and one of the two nonmuscle cytoskeletal actins. [provided by RefSeq, Jul 2008].

Application Details

Application Notes: WB 1:100-1000
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

References for anti-beta Actin antibody (ABIN724340)

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Huang, Zhu, Yi, Yan, Wei, Yang, Chen, Huang: "A novel TRAIL mutant-TRAIL-Mu3 enhances the antitumor effects by the increased affinity and the up-expression of DR5 in pancreatic cancer." in: Cancer chemotherapy and pharmacology, Vol. 82, Issue 5, pp. 829-838, (2019) (PubMed).

Lai, Jiang, Xie, Liu, Tang, Xiao, Gao, Jia, Bai: "Intestinal Pathology and Gut Microbiota Alterations in a Methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) Mouse Model of Parkinson's Disease." in: Neurochemical research, Vol. 43, Issue 10, pp. 1986-1999, (2019) (PubMed).

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Jia, Kong, Guo, Li, Quan: "Enhanced antitumor effect of combination of annexin A1 knockdown and bortezomib treatment in multiple myeloma in vitro and in vivo." in: Biochemical and biophysical research communications, Vol. 505, Issue 3, pp. 720-725, (2019) (PubMed).

Zhang, Li, Fu, Lin, Lin, Tu: "MiR-214 inhibits snakehead vesiculovirus (SHVV) replication by targeting host GS." in: Fish & shellfish immunology, Vol. 84, pp. 299-303, (2019) (PubMed).

Song, Ma, Hua, Xu, Li, Ju, Hou: "Functional role of RRS1 in breast cancer cell proliferation." in: Journal of cellular and molecular medicine, Vol. 22, Issue 12, pp. 6304-6313, (2019) (PubMed).

Feng, Su, Lin, Tu: "Development of a reverse genetics system for snakehead vesiculovirus (SHVV)." in: Virology, Vol. 526, pp. 32-37, (2019) (PubMed).

Cui, Xing, Huang, Li, Lu, Wang, Wang, Huang, Cheng, Hao, Peng, Liu, Dai, Yuan: "Signaling pathways involved in the expression of SZNF and the target genes binding with SZNF related to cyadox." in: Biomedicine & pharmacotherapy, Vol. 108, pp. 1879-1893, (2019) (PubMed).

Voogdt, Merchant, Wagenaar, van Putten: "Evolutionary Regression and Species-Specific Codon Usage of TLR15." in: Frontiers in immunology, Vol. 9, pp. 2626, (2019) (PubMed).

Zhang, Do, Chandimali, Lee, Mok, Kim, Kim, Kwon, Jeong: "Non-thermal plasma treatment improves chicken sperm motility via the regulation of demethylation levels." in: Scientific reports, Vol. 8, Issue 1, pp. 7576, (2019) (PubMed).

Pang, Wang, Ran, Lin, Wang, Guan, Yuan, Fang, Liu, Wang et al.: "Inhibitory Effect of Methotrexate on Rheumatoid Arthritis Inflammation and Comprehensive Metabolomics Analysis Using Ultra-Performance Liquid Chromatography-Quadrupole Time of Flight-Mass ..." in: International journal of molecular sciences, Vol. 19, Issue 10, (2019) (PubMed).

Zhang, Zhao, Li, Li: "Neuroprotective effects of matrix metalloproteinases in cerebral ischemic rats by promoting activation and migration of astrocytes and microglia." in: Brain research bulletin, Vol. 146, pp. 136-142, (2019) (PubMed).

Xia, Qu, Jia, He, Li, Zhao, Mao, Zhao: "Overexpression of Forkhead box C1 attenuates oxidative stress, inflammation and apoptosis in chronic obstructive pulmonary disease." in: Life sciences, Vol. 216, pp. 75-84, (2019) (PubMed).

Su, Tian, Liu, Ci, Lv: "Purinergic P2X7 receptor blockade mitigates alcohol-induced steatohepatitis and intestinal injury by regulating MEK1/2-ERK1/2 signaling and egr-1 activity." in: International immunopharmacology, Vol. 66, pp. 52-61, (2019) (PubMed).

Xiao, Hu, Song, Zhang, Dong, Jiang, Zhang, Yuan, Zhao: "Profile of melatonin and its receptors and synthesizing enzymes in cumulus-oocyte complexes of the developing sheep antral follicle-a potential estradiol-mediated mechanism." in: Reproductive biology and endocrinology : RB&E, Vol. 17, Issue 1, pp. 1, (2019) (PubMed).

Ommati, Heidari, Jamshidzadeh, Zamiri, Sun, Sabouri, Wang, Ahmadi, Javanmard, Seifi, Mousapour, Yeganeh: "Dual effects of sulfasalazine on rat sperm characteristics, spermatogenesis, and steroidogenesis in two experimental models." in: Toxicology letters, Vol. 284, pp. 46-55, (2018) (PubMed).

Liu, Liu, Bai, Zhang, Ma, Yang, Sun: "Hypoxia-induced activation of Twist/miR-214/E-cadherin axis promotes renal tubular epithelial cell mesenchymal transition and renal fibrosis." in: Biochemical and biophysical research communications, Vol. 495, Issue 3, pp. 2324-2330, (2018) (PubMed).

Target Details for beta Actin

Target: beta Actin (ACTB) (Actin, beta (ACTB))

Alternative Name: beta Actin (ACTB Products)

Background:

Synonyms: BRWS1, PS1TP5BP1, Actin, cytoplasmic 1, Beta-actin, ACTB

Background: Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells.

Gene ID: 60

UniProt: P60709

Pathways: Myometrial Relaxation and Contraction, Cell-Cell Junction Organization, Maintenance of Protein Location, Phototransduction