PP2A alpha/beta antibody (AA 205-309)
(2 references)-
- Target See all PP2A alpha/beta (PP2A A/B) products
- PP2A alpha/beta (PP2A A/B)
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Binding Specificity
- AA 205-309
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Reactivity
- Human, Mouse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This PP2A alpha/beta antibody is un-conjugated
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Application
- Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), ELISA, Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- Cross-Reactivity
- Human, Mouse
- Predicted Reactivity
- Rat,Dog,Cow,Pig,Chicken,Rabbit
- Purification
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human PP-2A
- Isotype
- IgG
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anti-PP2A alpha/beta (PP2A A/B) (pTyr307) antibody
PP2A A/B Reactivity: Human, Rat WB, IF (cc), IF (p), ELISA, IHC (p), IHC (fro) Host: Rabbit Polyclonal unconjugated
anti-PP2A alpha/beta (PP2A A/B) antibodyPP2A A/B Reactivity: Human, Mouse WB, IP Host: Mouse Monoclonal unconjugated
anti-PP2A alpha/beta (PP2A A/B) antibodyPP2A A/B Reactivity: Human, Mouse, Rat, Zebrafish (Danio rerio), Bat, Chicken, Cow, Dog, Drosophila melanogaster, Hamster, Horse, Insect, Monkey, Pig, Rabbit, Xenopus laevis WB, ELISA Host: Goat Polyclonal unconjugated
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- Application Notes
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WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Storage Comment
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- Expiry Date
- 12 months
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: "Feasibility of ?-Sheet Breaker Peptide-H102 Treatment for Alzheimer's Disease Based on ?-Amyloid Hypothesis." in: PLoS ONE, Vol. 9, Issue 11, pp. e112052, (2014) (PubMed).
: "Involvement of GSK3 and PP2A in ginsenoside Rb1's attenuation of aluminum-induced tau hyperphosphorylation." in: Behavioural brain research, Vol. 241, pp. 228-34, (2013) (PubMed).
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: "Feasibility of ?-Sheet Breaker Peptide-H102 Treatment for Alzheimer's Disease Based on ?-Amyloid Hypothesis." in: PLoS ONE, Vol. 9, Issue 11, pp. e112052, (2014) (PubMed).
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- Target
- PP2A alpha/beta (PP2A A/B)
- Alternative Name
- PP2A alpha / beta (PP2A A/B Products)
- Background
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Synonyms: RP-C, PP2Ac, PP2CA, PP2Calpha, Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform, PP2A-alpha, Replication protein C, PPP2CA
Background: PP2A is the major phosphatase for microtubule-associated proteins (MAPs). PP2A can modulate the activity of phosphorylase B kinase casein kinase 2, mitogen-stimulated S6 kinase, and MAP-2 kinase. Cooperates with SGOL2 to protect centromeric cohesin from separase-mediated cleavage in oocytes specifically during meiosis I (By similarity). Can dephosphorylate SV4 large T antigen and p53/TP53. Activates RAF1 by dephosphorylating it at 'Ser-259'.
- Gene ID
- 5515
- UniProt
- P67775
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