TDGF1 antibody

Catalog No. ABIN723351

Product Details anti-TDGF1 Antibody

Target: TDGF1 (Teratocarcinoma-Derived Growth Factor 1 (TDGF1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This TDGF1 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Cross-Reactivity: Human

Purification: Purified by Protein G.

Immunogen: KLH conjugated synthetic peptide derived from human CRIPTO/ Teratocarcinoma-derived growth factor 1

Clone: 1F10

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IF(IHC-P) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for TDGF1

Target: TDGF1 (Teratocarcinoma-Derived Growth Factor 1 (TDGF1))

Alternative Name: CRIPTO (TDGF1 Products)

Synonyms: CR antibody, CRGF antibody, CRIPTO antibody, CR1 antibody, cripto antibody, cb85 antibody, tdgf1 antibody, wu:fe01d04 antibody, zgc:109829 antibody, Cripto-1 antibody, cr1 antibody, cr1a antibody, frl-1 antibody, frl1 antibody, xcr1 antibody, TDGF1 antibody, tdgf3 antibody, cripto-3 antibody, teratocarcinoma-derived growth factor 1 antibody, teratocarcinoma-derived growth factor 1, member 3 L homeolog antibody, teratocarcinoma-derived growth factor 1, member 1 antibody, TDGF1 antibody, Tdgf1 antibody, tdgf1 antibody, tdgf1.3.L antibody, tdgf1.1 antibody

Background:

Synonyms: CRIPTO, CRIPT, CR, CRGF, Cripto 1, Cripto-1, Cripto 1 growth factor, Cripto-1 growth factor, Cripto1, Cripto1 growth factor, Epidermal growth factor like cripto protein CR1, Epidermal growth factor-like cripto protein CR1, TDGF 1, TDGF-1, TDGF1, Teratocarcinoma derived growth factor 1, Teratocarcinoma-derived growth factor 1, teratocarcinoma-derived growth factor 1 isoform 1 precursor, TDGF1_HUMAN.

Background: This gene encodes an epidermal growth factor-related protein that contains a cripto, FRL-1, and cryptic domain. The encoded protein is an extracellular, membrane-bound signaling protein that plays an essential role in embryonic development and tumor growth. Mutations in this gene are associated with forebrain defects. Pseudogenes of this gene are found on chromosomes 2, 3, 6, 8, 19 and X. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Mar 2010].

Gene ID: 6997

Pathways: EGFR Signaling Pathway