Recombinant HbA1c antibody (N-Term)
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- Target See all HbA1c Antibodies
- HbA1c (Glycated Hemoglobin HbA1c (HbA1c))
- Antibody Type
- Recombinant Antibody
- Binding Specificity
- N-Term
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This HbA1c antibody is un-conjugated
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Application
- ELISA
- Purpose
- Anti-HbA1c [1G8], Mouse IgG2a, kappa
- Specificity
- This antibody binds human hemoglobin glycated at the N-terminal valine of the hemoglobin β chain and does not cross react with non-glycated hemoglobin. Glycated hemoglobin is formed by the conjugation of a hexose sugar to the beta-chain of hemoglobin. Glycosylated hemoglobin A1c (HbA1c) levels are used as an indicator of average plasma glucose concentration in diabetic patients. Levels of more than 48 mmol/mol (6.5 % ) are used as a criterion for the diagnosis of diabetes. Higher levels of HbA1c are also associated with cardiovascular disease.
- Characteristics
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Original Species of Ab: Mouse
Original Format of Ab: IgG2a
- Purification
- Protein A affinity purified
- Immunogen
- The original antibody was generated by immunizing BALB/c mice with synthetic N-terminal glycopeptide (VHLTPEC) and KLH conjugate.
- Clone
- 1G8
- Isotype
- IgG2a kappa
- Top Product
- Discover our top product HbA1c Primary Antibody
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- Application Notes
- This antibody is recommended for detection of HbA1c levels in plasma and blood samples. The binding reactivity of this antibody towards HbA1c and non-glycated hemoglobin was done using indirect ELISA. The binding reactivity of this antibody to HbA1c was compared to commercially available anti-HbA1c antibody BM300-F7C2 and it was reported that this antibody showed better specificity for HbA1c (CN110724671).
- Restrictions
- For Research Use only
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- Concentration
- 1 mg/mL
- Buffer
- PBS with 0.02 % Proclin 300.
- Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Storage Comment
- Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
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- Target
- HbA1c (Glycated Hemoglobin HbA1c (HbA1c))
- Alternative Name
- HbA1c (HbA1c Products)
- Background
- GHb, A1C, HBB, hemoglobin A1c, glycosylated hemoglobin HbA1c, glycosylated hemoglobin, glycohemoglobin, glycated hemoglobin, haemoglobin, haemoglobin A1c, Hemoglobin subunit beta, Beta-globin, Hemoglobin beta chain
- UniProt
- P68871
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