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ADAM10 antibody (APC)

ADAM10 Reactivity: Human FACS Host: Mouse Monoclonal 11G2 APC
Catalog No. ABIN7540421
  • Target See all ADAM10 Antibodies
    ADAM10 (ADAM Metallopeptidase Domain 10 (ADAM10))
    Reactivity
    • 66
    • 29
    • 29
    • 1
    • 1
    • 1
    Human
    Host
    • 55
    • 11
    • 2
    • 1
    Mouse
    Clonality
    • 48
    • 21
    Monoclonal
    Conjugate
    • 31
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ADAM10 antibody is conjugated to APC
    Application
    • 43
    • 14
    • 14
    • 14
    • 13
    • 13
    • 7
    • 6
    • 6
    • 6
    • 4
    • 3
    • 1
    • 1
    Flow Cytometry (FACS)
    Purpose
    Anti-Hu CD156c APC
    Specificity
    The mouse monoclonal antibody 11G2 recognizes an extracellular/luminal epitope of CD156c, a type I transmembrane glycoprotein, serving as a zinc-dependent metalloprotease.
    No Cross-Reactivity
    Mouse
    Purification
    Purified antibody is conjugated with activated allophycocyanin (APC) under optimum conditions and unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.
    Immunogen
    Jurkat cells
    Clone
    11G2
    Isotype
    IgG1 kappa
    Top Product
    Discover our top product ADAM10 Primary Antibody
  • Application Notes
    Flow cytometry: The reagent is designed for analysis of human blood cells using 10 μL reagent / 100 μL of whole blood or 106 cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C
    Storage Comment
    Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
  • Target
    ADAM10 (ADAM Metallopeptidase Domain 10 (ADAM10))
    Alternative Name
    CD156c (ADAM10 Products)
    Background

    NCBI Full Gene Name: ADAM metallopeptidase domain 10

    Description: CD156c is a type I transmembrane glycoprotein with a zinc-dependent metalloprotease activity. It serves as an endopeptidase of broad specificity, which is expressed mainly in thymus, liver, and muscles. Its expression can be induced in inflamed central nervous system, and in arthritic tissues. CD156c is involved in multiple sclerosis-associated myelin degradation. It also solubilizes various membrane proteins, including CD23, CD44, CD126, CD171, ephrin-A2, and other.

    Other names: ADAM10, AD10, RAK, MADM, HsT18717

    Gene name: ADAM10

    Gene ID
    102
    UniProt
    O14672
    Pathways
    Notch Signaling, EGFR Signaling Pathway
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