ADAM10 antibody (APC)
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- Target See all ADAM10 Antibodies
- ADAM10 (ADAM Metallopeptidase Domain 10 (ADAM10))
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This ADAM10 antibody is conjugated to APC
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Application
- Flow Cytometry (FACS)
- Purpose
- Anti-Hu CD156c APC
- Specificity
- The mouse monoclonal antibody 11G2 recognizes an extracellular/luminal epitope of CD156c, a type I transmembrane glycoprotein, serving as a zinc-dependent metalloprotease.
- No Cross-Reactivity
- Mouse
- Purification
- Purified antibody is conjugated with activated allophycocyanin (APC) under optimum conditions and unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.
- Immunogen
- Jurkat cells
- Clone
- 11G2
- Isotype
- IgG1 kappa
- Top Product
- Discover our top product ADAM10 Primary Antibody
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- Application Notes
- Flow cytometry: The reagent is designed for analysis of human blood cells using 10 μL reagent / 100 μL of whole blood or 106 cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C
- Storage Comment
- Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
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- Target
- ADAM10 (ADAM Metallopeptidase Domain 10 (ADAM10))
- Alternative Name
- CD156c (ADAM10 Products)
- Background
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NCBI Full Gene Name: ADAM metallopeptidase domain 10
Description: CD156c is a type I transmembrane glycoprotein with a zinc-dependent metalloprotease activity. It serves as an endopeptidase of broad specificity, which is expressed mainly in thymus, liver, and muscles. Its expression can be induced in inflamed central nervous system, and in arthritic tissues. CD156c is involved in multiple sclerosis-associated myelin degradation. It also solubilizes various membrane proteins, including CD23, CD44, CD126, CD171, ephrin-A2, and other.
Other names: ADAM10, AD10, RAK, MADM, HsT18717
Gene name: ADAM10
- Gene ID
- 102
- UniProt
- O14672
- Pathways
- Notch Signaling, EGFR Signaling Pathway
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