CD180 antibody (AA 24-185)

Catalog No. ABIN7539705

Product Details anti-CD180 Antibody

Target: CD180 (CD180 Molecule (CD180))

Binding Specificity: AA 24-185

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD180 antibody is un-conjugated

Application: Flow Cytometry (FACS), Immunohistochemistry (IHC), ELISA, Immunocytochemistry (ICC)

Purpose: CD180 Antibody

Purification: Purified antibody

Immunogen: Purified recombinant fragment of human CD180 (AA: 24-185) expressed in E. Coli.

Clone: 1B3C4

Isotype: IgG1

Application Details

Application Notes:

ELISA: 1/10000

FCM: 1/200 - 1/400

ICC: 1/200 - 1/1000

Restrictions: For Research Use only

Handling

Buffer: Purified antibody in PBS with 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Target Details for CD180

Target: CD180 (CD180 Molecule (CD180))

Alternative Name: CD180 (CD180 Products)

Synonyms: Ly78 antibody, CD180 antibody, LY64 antibody, RP105 antibody, F630107B15 antibody, CD180 molecule antibody, CD180 antigen antibody, Cd180 antibody, CD180 antibody

Background:

Description: CD180 is a cell surface molecule consisting of extracellular leucine-rich repeats (LRR) and a short cytoplasmic tail. The extracellular LRR is associated with a molecule called MD-1 and form the cell surface receptor complex, RP105/MD-1. It belongs to the family of pathogen receptors, Toll-like receptors (TLR). RP105/MD1, by working in concert with TLR4, controls B cell recognition and signaling of lipopolysaccharide (LPS), a membrane constituent of Gram-negative bacteria.

Aliases: LY64, Ly78, RP105

Molecular Weight: 74.2 kDa

Gene ID: 4064

UniProt: Q99467

Pathways: Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades