Recombinant 4-1BB (Utomilumab Biosimilar) antibody

Catalog No. ABIN7538049

Product Details anti-4-1BB (Utomilumab Biosimilar) Antibody

Target: 4-1BB (Utomilumab Biosimilar)

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Human

Clonality: Monoclonal

Conjugate: This 4-1BB (Utomilumab Biosimilar) antibody is un-conjugated

Application: ELISA, Western Blotting (WB)

Purpose: Utomilumab Biosimilar - Anti-Human TNFRSF9 mAb - Research Grade

Characteristics: Antibody Type: IgG2 kappa

Purity: > 85%

Grade: Research Grade

Isotype: IgG2

Application Details

Restrictions: For Research Use only

Handling

Buffer: PBS pH 7.5

Storage: 4 °C,-20 °C

Storage Comment: 4°C for short term, -20°C for long term

Target Details for 4-1BB (Utomilumab Biosimilar)

Target: 4-1BB (Utomilumab Biosimilar)

Abstract: 4-1BB (Utomilumab Biosimilar) Products

Background: Utomilumab is a monoclonal antibody that binds to 4-IBB protein (also known as CD137 protein). 4-IBB protein is a receptor found in different immune cells such as helper T-cells, killer T-cells and natural killer cells. 4-IBB/CD137 protein is a costimulatory receptor whose activation results in a series of events that leads to cytokine secretion and effector functions. Hence, targeting CD137 protein has been linked to antitumor immunity response and overall tumor reduction. Indeed, once utomilumab is injected in the bloodstream its specific binding to CD137 protein stimulates the immune cells which, as a result, enhances the immune response against tumors.

CAS-No: 1417318-27-4