Recombinant 4-1BB (Utomilumab Biosimilar) antibody
Research Grade
Reactivity: Human
ELISA, WB
Host: Human
Monoclonal
unconjugated
Recombinant Antibody
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- Target See all 4-1BB (Utomilumab Biosimilar) products
- 4-1BB (Utomilumab Biosimilar)
- Antibody Type
- Recombinant Antibody
- Reactivity
- Human
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Host
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Human
- Expression System
- Mammalian cells
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Clonality
- Monoclonal
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Conjugate
- This 4-1BB (Utomilumab Biosimilar) antibody is un-conjugated
- Application
- ELISA, Western Blotting (WB)
- Purpose
- Utomilumab Biosimilar - Anti-Human TNFRSF9 mAb - Research Grade
- Characteristics
- Antibody Type: IgG2 kappa
- Purification
- Recombinant antibody expressed in mammalien cells and purified.
- Purity
- > 85%
- Grade
- Research Grade
- Isotype
- IgG2
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anti-4-1BB (Utomilumab Biosimilar) antibody
Research Grade Reactivity: Human ELISA Host: Human Monoclonal unconjugated Recombinant Antibody
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- Restrictions
- For Research Use only
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- Buffer
- PBS pH 7.5
- Storage
- 4 °C,-20 °C
- Storage Comment
- 4°C for short term, -20°C for long term
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- Target
- 4-1BB (Utomilumab Biosimilar)
- Abstract
- 4-1BB (Utomilumab Biosimilar) Products
- Background
- Utomilumab is a monoclonal antibody that binds to 4-IBB protein (also known as CD137 protein). 4-IBB protein is a receptor found in different immune cells such as helper T-cells, killer T-cells and natural killer cells. 4-IBB/CD137 protein is a costimulatory receptor whose activation results in a series of events that leads to cytokine secretion and effector functions. Hence, targeting CD137 protein has been linked to antitumor immunity response and overall tumor reduction. Indeed, once utomilumab is injected in the bloodstream its specific binding to CD137 protein stimulates the immune cells which, as a result, enhances the immune response against tumors.
- CAS-No
- 1417318-27-4
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