KLRG1 antibody

Catalog No. ABIN7536931

Product Details anti-KLRG1 Antibody

Target: KLRG1 (Killer Cell Lectin-Like Receptor Subfamily G, Member 1 (KLRG1))

Reactivity: Human

Host: Golden Syrian Hamster

Clonality: Monoclonal

Conjugate: This KLRG1 antibody is un-conjugated

Application: Flow Cytometry (FACS)

Purpose: Purified Anti-Human/Mouse KLRG-1 Antibody [2F1]

Purification: Purified

Clone: 2F1

Isotype: IgG

Application Details

Application Notes: Each lot of this antibody is quality control tested by flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 μg per 10^6 cells in 100 μL volume or 100 μL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: Phosphate buffered solution, pH 7.2, containing 0.09 % stabilizer.

Storage: 4 °C

Storage Comment: This product can be stored at 2-8°C for 12 months. Do not freeze.

Expiry Date: 12 months

Target Details for KLRG1

Target: KLRG1 (Killer Cell Lectin-Like Receptor Subfamily G, Member 1 (KLRG1))

Alternative Name: KLRG-1 (KLRG1 Products)

Synonyms: KLRG1 antibody, 2F1-Ag antibody, MAFA antibody, MAFA-L antibody, 2F1 antibody, CLEC15A antibody, MAFA-2F1 antibody, MAFA-LIKE antibody, killer cell lectin like receptor G1 antibody, killer cell lectin-like receptor subfamily G, member 1 antibody, KLRG1 antibody, Klrg1 antibody

Background: KLRG-1,MAFA, 2F1-Ag,Killer cell lectin-like receptor G1 (KLRG1) is the mouse homolog of the rat mast cell function-associated antigen (MAFA or 2F1-Ag).? KLRG1 is a type II membrane glycoprotein that was first identified on the surface of rat mast cell line RBL-2H3.? It is composed of a homodimer of glycosylated 30-38 kD subunits.? Mouse and human homologs of KLRG1 are expressed by subsets of NK cells and lymphokine-activated killer (LAK) cells but not mast cells.? KLRG1 is also expressed on subsets of CD8+?and CD4+?cells, including CD4+?and CD8+?effector/memory cells, potent regulatory CD4+?T cells.? KLRG1 may be involved in regulating NK cell homeostasis.? KLRG2 was found to recognize cadherins and thus inhibit immune responses by regulating the effector function and the developmental processes of NK and T cells.

Gene ID: 10219, 50928

UniProt: Q96E93, O88713